一个恶性贫血并发小β-地中海贫血的病例。

IF 2.1 Q3 HEMATOLOGY

Journal of Blood Medicine Pub Date : 2024-08-07 eCollection Date: 2024-01-01 DOI:10.2147/JBM.S473075

Fuzhen Yuan, Zhenhua Huang, Dingye Yao, Junsheng Sun

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引用次数: 0

摘要

维生素 B12 是人体各种功能所必需的，缺乏维生素 B12 可能会导致血液病。我们报告了一例病例，一名 65 岁的女性因味觉减退和舌头疼痛入院。她的血清中维生素 B12 水平下降。然而，她的全血细胞计数并未显示任何大红细胞增多症的证据，相反，她的平均血球容积却很低。基因测序显示她患有小β地中海贫血症，这可能掩盖了维生素 B12 缺乏症的巨幼红细胞症特征。

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A Case of Pernicious Anemia with Concurrent Beta-Thalassemia Minor.

Vitamin B₁₂ is essential for various bodily functions, and its deficiency may cause hematological manifestations. We report a case of a previously healthy 65-year-old female who was admitted to our hospital with reduced sense of taste and painful tongue. The serum level of vitamin B₁₂ was decreased. However, her complete blood count did not show any evidence of macrocytosis, instead, her mean corpuscular volume was low. Gene sequencing indicated an β-thalassemia minor and that probably masked the megaloblastic features of vitamin B₁₂ deficiency.

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来源期刊

Journal of Blood Medicine HEMATOLOGY-

CiteScore

3.50

自引率

0.00%

发文量

审稿时长

16 weeks

期刊介绍： The Journal of Blood Medicine is an international, peer-reviewed, open access, online journal publishing laboratory, experimental and clinical aspects of all topics pertaining to blood based medicine including but not limited to: Transfusion Medicine (blood components, stem cell transplantation, apheresis, gene based therapeutics), Blood collection, Donor issues, Transmittable diseases, and Blood banking logistics, Immunohematology, Artificial and alternative blood based therapeutics, Hematology including disorders/pathology related to leukocytes/immunology, red cells, platelets and hemostasis, Biotechnology/nanotechnology of blood related medicine, Legal aspects of blood medicine, Historical perspectives. Original research, short reports, reviews, case reports and commentaries are invited.