NEC 的临床表现、诊断、处理和益生菌的预防效果:叙述性综述。

IF 1.3 Q3 PEDIATRICS
Giuseppe De Bernardo, ZIello Carla, Parisi Grazia, Vecchione Carolina, Fattorusso Valentina, Spadarella Simona, Giordano Maurizio, Buonocore Giuseppe, Perrone Serafina
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引用次数: 0

摘要

早产儿是肠道菌群失调的高危人群,也是败血症和坏死性小肠结肠炎的易感人群。坏死性小肠结肠炎是一种因肠道屏障改变、免疫系统不成熟和肠道菌群失调而引起的并发症多、死亡率高的疾病。低胎龄儿、低出生体重和过早使用抗生素也是易患此病的因素。相反,母乳和益生菌是提供肠道平衡和微生物组调节的保护因素。在这篇微型综述中,我们分析了益生菌对早产儿坏死性小肠结肠炎发病的保护作用。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Clinical Picture, Diagnosis, Management of NEC, and Effects of Probiotics on its Prevention: A Narrative Review.

Preterm newborns represent a population at risk of developing intestinal dysbiosis as well as being predisposed to sepsis and Necrotizing Enterocolitis. Necrotizing Enterocolitis is a condition burdened by many complications and mortality due to an alteration of the intestinal barrier, an immaturity of the immune system, and intestinal dysbiosis. Low gestational age at birth, low birth weight, and early use of antibiotics are other predisposing factors. Instead, breast milk and probiotics are protective factors in providing intestinal homeostasis and microbiome regulation. In this mini-review, we analysed the protective role of probiotics in the onset of Necrotizing Enterocolitis in preterm populations.

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来源期刊
CiteScore
4.30
自引率
0.00%
发文量
66
期刊介绍: Current Pediatric Reviews publishes frontier reviews on all the latest advances in pediatric medicine. The journal’s aim is to publish the highest quality review articles dedicated to clinical research in the field. The journal is essential reading for all researchers and clinicians in pediatric medicine.
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