胰腺癌患者精神并发症的预测因素:回顾性队列研究

IF 16.4 1区 化学 Q1 CHEMISTRY, MULTIDISCIPLINARY
Lewei Liu, Shuo Chen
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引用次数: 0

摘要

背景:相关调查显示,胰腺癌患者的精神并发症发生率很高。虽然一些研究探讨了影响胰腺癌患者心理并发症的因素,但一些在其他人群中得到验证的因素尚未在胰腺癌人群中得到证实。本研究旨在探讨胰腺癌患者精神并发症的预测因素:方法:对温州医科大学附属乐清市人民医院2021年1月至2022年1月收治的胰腺癌患者进行回顾性分析。护士使用基于《精神疾病诊断与统计手册》(DSM-IV)的结构化临床访谈(SCID-I)评估住院期间(基线)和治疗开始后 3 个月的精神并发症发生率。二元逻辑回归用于确定精神并发症的预测因素:本研究共纳入 80 名患者,其中 8 名患者在基线时被诊断为精神并发症。其余 72 名患者中,有 8 名患者(11.11%)在随访 3 个月时出现了新的精神并发症。性别(Odds Ratio (OR) = 1.674,p = 0.019)、月收入(OR = 1.735,p = 0.023)和悲伤(M.D. Anderson 症状量表(MDASI))(OR = 1.804,p = 0.001)都是胰腺癌患者精神并发症的预测因素:结论:性别、月收入和 MDASI 评分是胰腺癌患者精神并发症的预测因素。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Predictors of Psychiatric Complications in Patients with Pancreatic Cancer: A Retrospective Cohort Study.

Background: The relevant survey has shown a high incidence of psychiatric complications in patients with pancreatic cancer. While some studies have explored the factors influencing psychological complications in pancreatic cancer patients, some factors validated in other populations have not been confirmed in the pancreatic cancer population. This study aims to explore the predictors of psychiatric complications in patients with pancreatic cancer.

Methods: Patients with pancreatic cancer admitted to Yueqing People's Hospital Affiliated to Wenzhou Medical University, from January 2021 to January 2022 were retrospectively analyzed. The structured clinical interview (SCID-I) based on Diagnostic and Statistical Manual of Mental Disorders (DSM-IV) was used by nurses to assess the incidence of psychiatric complications during hospitalization (baseline) and 3 months after the start of treatment. Binary logistic regression was used to identify predictors of psychiatric complications.

Results: 80 patients were enrolled in this study and 8 patients were diagnosed with psychiatric complications at base line. Among the rest 72 patients, 8 patients (11.11%) had new-onset psychiatric complications at 3-month follow-up. Gender (Odds Ratio (OR) = 1.674, p = 0.019), monthly income (OR = 1.735, p = 0.023) and sadness (M.D. Anderson Symptom Inventory (MDASI)) (OR = 1.804, p = 0.001) were all predictors for psychiatric complications in patients with pancreatic cancer.

Conclusions: Gender, monthly income and MDASI score are predictors of psychiatric complications in patients with pancreatic cancer.

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来源期刊
Accounts of Chemical Research
Accounts of Chemical Research 化学-化学综合
CiteScore
31.40
自引率
1.10%
发文量
312
审稿时长
2 months
期刊介绍: Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.
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