一例辐射照射后发生的未分化多形性直肠肉瘤。

IF 0.8 Q4 GASTROENTEROLOGY & HEPATOLOGY

Clinical Journal of Gastroenterology Pub Date : 2024-12-01 Epub Date: 2024-08-09 DOI:10.1007/s12328-024-02026-6

Makoto Eizuka, Yosuke Toya, Shun Yamada, Tomofumi Oizumi, Shunichi Yanai, Norihiko Kudara, Naoki Yanagawa, Tamotsu Sugai, Takayuki Matsumoto

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引用次数: 0

摘要

一名 72 岁的男子因复发性直肠息肉转诊至我院进行详细检查。他曾在 66 岁时接受过前列腺癌手术和放射治疗，70 岁时接受过直肠息肉内镜切除术。结肠镜检查发现一个被易碎粘膜包围的半截状病灶，在正电子发射断层扫描-计算机断层扫描中呈阳性。对内镜下切除的息肉进行组织病理学检查，发现非典型细胞增生，具有强烈的多形性或纺锤形形态，免疫组化结果与未分化多形性肉瘤相符。我们将此病例诊断为肉瘤，推测与放射性直肠炎有关。

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A case of undifferentiated pleomorphic rectal sarcoma occurring after radiation exposure.

A 72 year-old man was referred to our hospital for a detailed examination of a recurrent rectal polyp. He had past histories of surgery and radiation therapy for prostate cancer at the age of 66 and endoscopic excision of a rectal polyp at the age of 70. Colonoscopy revealed a semi-pedunculated lesion surrounded by friable mucosa, which was positive under positron-emission tomography-computed tomography. Histopathological examination of the endoscopically excised polyp revealed proliferation of atypical cells, characterized by strong pleomorphic or spindle morphology, which was immunohistochemically compatible with undifferentiated pleomorphic sarcoma. We diagnosed this case as sarcoma presumably associated with radiation proctitis.

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来源期刊

Clinical Journal of Gastroenterology GASTROENTEROLOGY & HEPATOLOGY-

CiteScore

2.00

自引率

0.00%

发文量

182

期刊介绍： The journal publishes Case Reports and Clinical Reviews on all aspects of the digestive tract, liver, biliary tract, and pancreas. Critical Case Reports that show originality or have educational implications for diagnosis and treatment are especially encouraged for submission. Personal reviews of clinical gastroenterology are also welcomed. The journal aims for quick publication of such critical Case Reports and Clinical Reviews.