Michaella Alexandrou, Athanasios Rempakos, Deniz Mutlu, Ahmed Al Ogaili, Pedro E P Carvalho, Dimitrios Strepkos, James W Choi, Paul Poommipanit, Khaldoon Alaswad, Mir Babar Basir, Rhian Davies, Farouc A Jaffer, Phil Dattilo, Anthony H Doing, Lorenzo Azzalini, Nazif Aygul, Raj H Chandwaney, Brian K Jefferson, Sevket Gorgulu, Jaikirshan J Khatri, Laura D Young, Oleg Krestyaninov, Dmitrii Khelimskii, Jarrod Frizzell, Omer Goktekin, James D Flaherty, Daniel R Schimmel, Keith H Benzuly, Mahmut Uluganyan, Ramazan Ozdemir, Yousif Ahmad, Bavana V Rangan, Olga C Mastrodemos, M Nicholas Burke, Konstantinos Voudris, Yader Sandoval, Emmanouil S Brilakis
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引用次数: 0
摘要
背景:外周动脉疾病(PAD)对慢性全闭塞(CTO)经皮冠状动脉介入治疗(PCI)结果的影响尚未得到充分研究:外周动脉疾病(PAD)对慢性全闭塞(CTO)经皮冠状动脉介入治疗(PCI)结果的影响尚未得到充分研究:我们使用 PROGRESS-CTO 登记的数据分析了 PAD 与 CTO-PCI 治疗效果的关系,这些数据来自 2012 年至 2023 年期间在 47 个中心进行的手术:在研究期间接受 CTO PCI 的 12 961 名患者中,PAD 患病率为 13.9%(1802 人)。PAD患者年龄较大,更有可能是吸烟者,血脂异常、糖尿病、脑血管疾病、高血压、既往心肌梗死、PCI和冠状动脉旁路移植手术的发生率较高。他们的 PROGRESS-CTO (1.35 vs 1.22; P < .001) 和 J-CTO (2.63 vs 2.33; P < .001) 评分更高,病变长度更长,血管造影特征更复杂。与无 PAD 患者相比,他们的入路部位更可能是双股动脉(33.6% vs 30.9%; P = .024)。PAD患者的技术成功率(82.9% vs 87.7%;P < .001)和手术成功率(80.5% vs 86.6%;P < .001)较低,而主要不良心血管事件(MACE)的发生率较高(3.1% vs 1.8%;P < .001),死亡率(0.8% vs 0.4%;P = .034)、急性心肌梗死率(0.9% vs 0.4%;P = .010)和穿孔率(6.6% vs 4.5%;P < .001)更高。在多变量分析中,PAD 与较高的 MACE(几率比 [OR]:1.53;95% CI,1.01-2.26;P = .038)和较低的技术成功率(OR:0.82;95% CI,0.69-0.99;P = .039)相关:结论:接受CTO PCI治疗的PAD患者合并症负担更高、CTO更复杂、MACE更高、技术成功率更低。
期刊介绍:
The Journal of Invasive Cardiology will consider for publication suitable articles on topics pertaining to the invasive treatment of patients with cardiovascular disease.