晚期前列腺癌的单细胞分析

IF 12.1 1区医学 Q1 UROLOGY & NEPHROLOGY

Nature Reviews Urology Pub Date : 2024-08-09 DOI:10.1038/s41585-024-00933-4

Louise Lloyd

引用次数: 0

摘要

对耐药前列腺癌的单细胞分析表明，各种晚期疾病类型（包括耐阉割和神经内分泌前列腺癌）的细胞状态之间存在高度异质性。据观察，PSMA、STEAP1、STEAP2、TROP2、CEACAM5 和 DLL3 的表达在基因调控网络的一个子集中有所不同。因此，基因调控网络可用于识别细胞状态，从而提高诊断的准确性。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Nature Reviews Urology 医学-泌尿学与肾脏学

CiteScore

12.50

自引率

2.60%

发文量

123

审稿时长

6-12 weeks

期刊介绍： Nature Reviews Urology is part of the Nature Reviews portfolio of journals.Nature Reviews' basic, translational and clinical content is written by internationally renowned basic and clinical academics and researchers. This journal targeted readers in the biological and medical sciences, from the postgraduate level upwards, aiming to be accessible to professionals in any biological or medical discipline. The journal features authoritative In-depth Reviews providing up-to-date information on topics within a field's history and development. Perspectives, News & Views articles, and the Research Highlights section offer topical discussions and opinions, filtering primary research from various medical journals. Covering a wide range of subjects, including andrology, urologic oncology, and imaging, Nature Reviews provides valuable insights for practitioners, researchers, and academics within urology and related fields.