接受雌激素治疗的变性女性接受 PSA 筛查的效用

IF 12.1 1区 医学 Q1 UROLOGY & NEPHROLOGY
Maria Chiara Masone
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引用次数: 0

摘要

在发表于《美国医学会杂志》(JAMA)上的一项研究中,作者评估了接受雌激素治疗的变性女性队列中的前列腺特异性抗原(PSA)值,因为在这一人群中,PSA水平(受雄激素调节)可能会发生变化。该队列是通过对退伍军人健康管理局记录中随机抽取的 1000 名年龄≥40 岁的患者进行病历审查而建立的。共有 210 名患者符合纳入标准,其中包括确认变性女性身份、未确诊前列腺癌以及接受雌激素治疗。该队列中的 PSA 水平中位数为 0.02 纳克/毫升(四分位距为 0-0.2),远低于类似研究报告的 PSA 水平中位数(1 纳克/毫升,四分位距为 0.6-1.9),这些研究的对象包括未确诊前列腺癌的顺性别男性。此外,36% 的女性检测不到 PSA。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Utility of PSA screening in transgender women receiving oestrogens
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来源期刊
Nature Reviews Urology
Nature Reviews Urology 医学-泌尿学与肾脏学
CiteScore
12.50
自引率
2.60%
发文量
123
审稿时长
6-12 weeks
期刊介绍: Nature Reviews Urology is part of the Nature Reviews portfolio of journals.Nature Reviews' basic, translational and clinical content is written by internationally renowned basic and clinical academics and researchers. This journal targeted readers in the biological and medical sciences, from the postgraduate level upwards, aiming to be accessible to professionals in any biological or medical discipline. The journal features authoritative In-depth Reviews providing up-to-date information on topics within a field's history and development. Perspectives, News & Views articles, and the Research Highlights section offer topical discussions and opinions, filtering primary research from various medical journals. Covering a wide range of subjects, including andrology, urologic oncology, and imaging, Nature Reviews provides valuable insights for practitioners, researchers, and academics within urology and related fields.
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