成人体脂质量分布与骨矿物质密度之间的线性和非线性关系:2011-2018年美国国家健康调查(NHANES)。

IF 4.3 2区 医学 Q1 MEDICINE, GENERAL & INTERNAL
Xiaohua Zhang , Juan Zhang , Zhaoyue Shang , Yanlin Duan , Yongliang Du , Bo Kan , Shuman Yang
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引用次数: 0

摘要

目的:体脂量与骨矿物质密度(BMD)之间的关系仍存在争议。本研究旨在探讨美国成年人的体脂量与 BMD 之间的线性或非线性关系:这项横断面研究在 2011 年至 2018 年的全国健康与营养调查中确定了 18 岁或以上的成年人。在调整协变量后,通过广义线性模型检验了不同性别的体脂质量与 BMD 之间的线性关系,并通过广义相加模型和分片线性回归模型探讨了潜在的非线性关系:研究对象包括 4691 名男性(占样本总数的 57.9%)和 3417 名女性(占样本总数的 42.1%)。在男性和女性中,我们发现睾丸或全身脂肪量与腰椎 BMD 之间呈负相关,而阑尾、睾丸、妇科或全身脂肪量与全身 BMD 之间呈正相关(所有 P 均为非线性非线性结论:体脂量与腰椎 BMD 呈线性负相关,但与全身 BMD 呈正相关。男性体脂量与腰椎 BMD 呈 U 型关系,女性体脂量与腰椎和全身 BMD 呈倒 U 型关系。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Linear and non-linear relationships between body fat mass distribution and bone mineral density in adults: The NHANES, 2011–2018

Objective

The relationship between body fat mass and bone mineral density (BMD) remains controversial. This research aimed to explore the linear or non-linear relationship between body fat mass and BMD among adults in the United States.

Methods

This cross-sectional study identified adults aged 18 years or older in the National Health and Nutrition Examination Survey from 2011 to 2018. After adjusting for covariates, linear relationships between body fat mass and BMD in different genders were tested by generalized linear models, and potential non-linear relationships were explored by generalized additive models and piecewise linear regression models.

Results

The research included 4691 (57.9% of the total sample) males and 3417 (42.1% the of total sample) females. In both males and females, we found a negative association between android or total body fat mass and lumbar spine BMD and a positive association between appendicular, android, gynoid, or total body fat mass and whole body BMD (all P < 0.05). The relationships between body fat mass in all regions and lumbar spine BMD were U-shaped in males and inverted U-shaped in females (all P non-linear < 0.05). Inverted U-shaped relationships existed between body fat mass in all regions and whole body BMD in females (all P non-linear < 0.05).

Conclusions

Body fat mass was negatively and linearly associated with lumbar spine BMD, but positively associated with whole body BMD. Body fat mass had a U-shaped relationship with lumbar spine BMD in males and an inverted U-shaped association with lumbar spine and whole body BMD in females.

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来源期刊
Preventive medicine
Preventive medicine 医学-公共卫生、环境卫生与职业卫生
CiteScore
7.70
自引率
3.90%
发文量
0
审稿时长
42 days
期刊介绍: Founded in 1972 by Ernst Wynder, Preventive Medicine is an international scholarly journal that provides prompt publication of original articles on the science and practice of disease prevention, health promotion, and public health policymaking. Preventive Medicine aims to reward innovation. It will favor insightful observational studies, thoughtful explorations of health data, unsuspected new angles for existing hypotheses, robust randomized controlled trials, and impartial systematic reviews. Preventive Medicine''s ultimate goal is to publish research that will have an impact on the work of practitioners of disease prevention and health promotion, as well as of related disciplines.
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