躁狂症检查表-33:青少年精神病混合样本的风险分层和因子结构。

IF 2.8 2区 医学 Q2 PSYCHIATRY
Miriam Gerstenberg, Lukasz Smigielski, Anna M Werling, Maria E Dimitriades, Christoph U Correll, Susanne Walitza, Jules Angst
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引用次数: 0

摘要

背景:33项躁狂症核对表(HCL-33)已被证明可以区分青少年双相情感障碍(BD)和单相抑郁症。为了研究 HCL-33 作为常规诊断筛查工具的实用性,有必要对混合精神病样本中被检测者的频率和精神病理学特征进行更多研究:方法:在一个混合精神病样本中,285 名儿童和青少年(12-18 岁)完成了 HCL-33、儿童抑郁量表、贝克焦虑量表和优势与困难问卷。根据建议的 HCL-33 临界分数(≥ 18 分),有抑郁症状的个体被分为有抑郁症风险组和无抑郁症风险组。结果:20.6%的样本符合BD高危标准。与非高危人群(107 人)相比,这些人(55 人)年龄更大、更焦虑、行为问题更多。研究人员采用了双因素和三因素模型,其中因素 1("主动相关")相同。在三因素模型中,因素 2("冒险/易怒")被分为 2a("易怒-无常")和 2b("外向-抑制")。较高的因子 2 和 2a 分值与一系列较严重的症状(即抑郁、焦虑、多动)相关,而较高的因子 1 和 2b 分值则分别与较多的情绪和行为问题相关。51.7%的样本报告躁狂症状对日常功能产生了负面影响:局限性:横断面设计,数据收集仅限于一家心理健康服务机构:HCL-33可能是改进诊断的有用工具,尤其是对于有抑郁症状并伴有焦虑症状和行为问题的青少年。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Hypomania-Checklist-33: risk stratification and factor structure in a mixed psychiatric adolescent sample.

Background: The 33-item Hypomania Checklist (HCL-33) has been shown to distinguish between adolescent bipolar disorder (BD) and unipolar depression. To investigate the utility of the HCL-33 as a screening tool in routine diagnostics, the frequency and psychopathological characteristics of detected individuals in a mixed psychiatric sample necessitate more examination.

Methods: The HCL-33, Children's Depression Inventory, Beck's Anxiety Inventory, and Strengths and Difficulties Questionnaire were completed by 285 children and adolescents (12-18 years) in a mixed psychiatric sample. Applying the proposed HCL-33 cut-off score of ≥ 18, individuals with depressive symptoms were divided into at-risk or not at-risk for BD groups. The factorial structure, sum and factor score correlations with psychopathology, and impact on daily functioning were assessed.

Results: 20.6% of the sample met at-risk criteria for BD. These individuals (n = 55) were older, more anxious, and showed more conduct problems vs the not at-risk group (n = 107). A two- and a three-factor model were pursued with the same Factor 1 ("active-elated"). Factor 2 ("risk-taking/irritable") was separated into 2a ("irritable-erratic") and 2b ("outgoing-disinhibited") in the three-factor model. Whereas higher Factor 2 and 2a scores correlated with a broad range of more severe symptomatology (i.e., depression, anxiety, hyperactivity), higher Factor 1 and 2b scores correlated with more emotional and conduct problems, respectively. 51.7% of the sample reported a negative impact from hypomanic symptoms on daily functioning.

Limitations: Cross-sectional design and data collection in a single mental health service.

Conclusions: The HCL-33 may be a useful tool to improve diagnostics, especially in adolescents with depressive symptoms additionally presenting with anxious symptoms and conduct problems.

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来源期刊
International Journal of Bipolar Disorders
International Journal of Bipolar Disorders Medicine-Psychiatry and Mental Health
CiteScore
6.70
自引率
5.00%
发文量
26
审稿时长
13 weeks
期刊介绍: The International Journal of Bipolar Disorders is a peer-reviewed, open access online journal published under the SpringerOpen brand. It publishes contributions from the broad range of clinical, psychological and biological research in bipolar disorders. It is the official journal of the ECNP-ENBREC (European Network of Bipolar Research Expert Centres ) Bipolar Disorders Network, the International Group for the study of Lithium Treated Patients (IGSLi) and the Deutsche Gesellschaft für Bipolare Störungen (DGBS) and invites clinicians and researchers from around the globe to submit original research papers, short research communications, reviews, guidelines, case reports and letters to the editor that help to enhance understanding of bipolar disorders.
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