一例原发灶不明的癌症伴有乳糜胸。

IF 1 4区医学 Q3 MEDICINE, GENERAL & INTERNAL

Internal Medicine Pub Date : 2025-03-15 Epub Date: 2024-08-08 DOI:10.2169/internalmedicine.3988-24

Emi Tanaka, Naohiro Oda, Tsuneyoshi Ogawa, Ichiro Takata, Masako Terao, Toru Ueki

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引用次数: 0

摘要

一名 56 岁的男子因劳累时呼吸困难两个月来我院就诊。发现双侧胸腔积液，仔细检查发现有乳糜胸，包括腺癌。全身检查无法确定原发肿瘤。因此，患者被诊断为原发灶不明的癌症（CUP），并伴有乳糜胸。对 CUP 进行了化疗，对乳糜胸和乳糜腹水进行了胸腔穿刺、胸膜穿刺、腹水穿刺和营养治疗。虽然引流次数和肿瘤标志物水平（CA19-9、DUPAN-2 和 Span-1）暂时下降，但病情控制恶化，患者在最初诊断 12 个月后死亡。

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Cancer of Unknown Primary Presenting with Chylothorax.

A 56-year-old man presented to our hospital with dyspnea on exertion for two months. Bilateral pleural effusions were found, and a close examination revealed a chylothorax, including adenocarcinoma. The primary tumor could not be identified by systemic examination. Therefore, the patient was diagnosed with cancer of unknown primary (CUP) presenting with chylothorax. Chemotherapy was administered for CUP, and thoracentesis, pleurodesis, ascites puncture, and nutritional therapy were performed for chylothorax and chylous ascites. Although drainage frequency and tumor marker levels (CA19-9, DUPAN-2, and Span-1) temporarily decreased, disease control deteriorated, and the patient died 12 months after the initial diagnosis.

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来源期刊

Internal Medicine 医学-医学：内科

CiteScore

1.90

自引率

8.30%

发文量

审稿时长

2.2 months

期刊介绍： Internal Medicine is an open-access online only journal published monthly by the Japanese Society of Internal Medicine. Articles must be prepared in accordance with "The Uniform Requirements for Manuscripts Submitted to Biomedical Journals (see Annals of Internal Medicine 108: 258-265, 1988), must be contributed solely to the Internal Medicine, and become the property of the Japanese Society of Internal Medicine. Statements contained therein are the responsibility of the author(s). The Society reserves copyright and renewal on all published material and such material may not be reproduced in any form without the written permission of the Society.