晚年痴呆症的临界初潮年龄以及教育和社会经济地位的作用。

IF 1.6 4区 心理学 Q3 PSYCHOLOGY, DEVELOPMENTAL
Sotiria Moza, Nikolaos Scarmeas, Mary Yannakoulia, Efthimios Dardiotis, Georgios M Hadjigeorgiou, Paraskevi Sakka, Mary H Kosmidis
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引用次数: 0

摘要

月经期间的雌激素暴露与晚年神经保护有关。我们探讨了对年龄敏感的月经初潮对老年认知的影响,以及社会经济地位和教育程度的影响。我们比较了 1082 名老年妇女(平均年龄 = 72.69 (5.48))的神经心理学表现、童年、青春期早期、中期和晚期初潮以及痴呆症的患病率、严重程度和类型,包括教育和社会经济地位的影响。与 15-17 岁月经初潮者相比,调整协变量后,11-14 岁月经初潮者的老年记忆力、执行力和整体认知功能更佳,教育和社会经济地位对认知的积极影响也更强。我们发现,雌激素对神经保护作用的关键年龄窗口在青春期早期,这使得初潮较晚的女性认知能力下降的风险更高。成年后社会经济地位和教育的影响应是未来研究的重点。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Critical menarche age for late-life dementia and the role of education and socioeconomic status.

Estrogen exposure during menstrual years has been associated with late-life neuroprotection. We explored the presence of an age-sensitive menarche window for cognition in old age and the impact of socioeconomic status and education. We compared neuropsychological performance of 1082 older women [MeanAGE = 72.69 (5.48)] with menarche in childhood, early-, mid-, and late-adolescence and dementia prevalence, severity, and type, including the effects of education and socioeconomic status. Adjusting for covariates, menarche at 11-14 years of age was associated with better memory, executive and global cognitive functioning in old age, and stronger positive effects of education and socioeconomic status on cognition than those with menarche at 15-17 years. We found a critical age window for the neuroprotective effects of estrogens during early adolescence, putting women with later menarche at higher risk for cognitive decline. Effects of socioeconomic status and education in adulthood should be a focus of future research.

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来源期刊
CiteScore
4.30
自引率
5.30%
发文量
52
期刊介绍: The purposes of Aging, Neuropsychology, and Cognition are to (a) publish research on both the normal and dysfunctional aspects of cognitive development in adulthood and aging, and (b) promote the integration of theories, methods, and research findings between the fields of cognitive gerontology and neuropsychology. The primary emphasis of the journal is to publish original empirical research. Occasionally, theoretical or methodological papers, critical reviews of a content area, or theoretically relevant case studies will also be published.
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