[梗塞代码计划单中心登记分析:回顾性队列]。

Otoniel Toledo-Salinas, Saira Sanjuana Gómez-Flores, Ernesto García-Hernández, Verónica Armenta-Pérez, Andrés García-Rincón
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引用次数: 0

摘要

背景:急性冠状动脉综合征(ACS急性冠状动脉综合征(ACS)是冠心病最严重的表现。梗死代码(西班牙语首字母缩写为 CI:Código Infarto)计划旨在改善对这些患者的护理:描述冠心病监护病房(CCU)中 CI 项目的临床表现和结果:分析了一家冠心病监护病房连续 5 年的数据库记录。研究对象包括确诊为急性心肌梗死(ACS)的患者。使用Student's t、Mann-Whitney U和秩方检验比较有ST段抬高和无ST段抬高的急性心肌梗死组。我们计算了心血管风险因素对死亡率的相对风险(RR)和 95% 置信区间(95% CI):共分析了 4678 名受试者,其中 78.7% 为男性,平均年龄为 63 岁(± 10.7)。80.76%的患者为急性心肌梗死,ST段抬高呈阳性,60.8%的患者接受了纤维蛋白溶解治疗。81.4%的患者接受了经皮冠状动脉介入治疗,82.5%的患者治疗成功。被归类为CI的患者死亡率为6.8%对11.7%,P = 0.001。侵入性机械通气的RR为26.58(95% CI:20.61-34.3),循环休克的RR为20.86(95% CI:16.16-26.93):CI项目将死亡率降低了4.9%。早期纤维蛋白溶解和成功的冠状动脉造影是CCU内死亡率的保护因素。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
[Analysis of the unicentric registry of the Infarction Code program: retrospective cohort].

Background: Acute coronary syndrome (ACS) is the most serious manifestation of coronary heart disease. The Infarction Code (according to its initialism in Spanish, CI: Código Infarto) program aims to improve the care of these patients.

Objective: To describe the clinical presentation and outcomes of CI program in a coronary care unit (CCU).

Material and methods: A database of a CCU with 5 years of consecutive records was analyzed. Patients diagnosed with ACS were included. The groups with acute myocardial infarction with and without ST-segment elevation were compared using Student's t, Mann-Whitney U and chi-squared tests. We calculated the relative risk (RR) and 95% confidence intervals (95% CI) of cardiovascular risk factors for mortality.

Results: A total of 4678 subjects were analyzed, 78.7% men, mean age 63 years (± 10.7). 80.76% presented acute myocardial infarction with positive ST-segment elevation and fibrinolytic was granted in 60.8% of cases. Percutaneous coronary intervention was performed in 81.4% of patients, which was successful in 82.5% of events. Patients classified as CI presented mortality of 6.8% vs. 11.7%, p = 0.001. Invasive mechanical ventilation had an RR of 26.58 (95% CI: 20.61-34.3) and circulatory shock an RR of 20.86 (95% CI: 16.16-26.93).

Conclusions: The CI program decreased mortality by 4.9%. Early fibrinolysis and successful coronary angiography are protective factors for mortality within CCU.

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