独立 iStent 植入术与联合 iStent 植入术和超声乳化术的一年期比较分析。

IF 1.4 4区 医学 Q3 OPHTHALMOLOGY
Phong Yue Khoo, Seng Fai Tang, Chenshen Lam, Teck Chee Cheng, Norshamsiah Md Din
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引用次数: 0

摘要

目的:评估开角型青光眼(OAG)患者单独植入 iStent 或联合超声乳化术的实际疗效和安全性:这是一项回顾性观察研究,研究对象为接受独立或联合 iStent 手术的开角型青光眼患者。纳入标准包括年龄超过 18 岁且眼底检查显示开角。排除标准包括之前接受过切开青光眼手术、数据缺失或随访时间少于 6 个月。主要结果是一年后两组患者的手术成功率。次要结果包括眼压降低和药物使用的差异:结果:我们共纳入了 48 例原发性(44 例)和继发性 OAG(4 例)患者。19只眼睛接受了独立手术,29只眼睛接受了联合手术。卡普兰-米尔分析显示,一年后,31.3%的患者手术总体成功。联合组的合格成功率高于独立组[62.5%(10 眼)vs 27.3%(3 眼),P = 0.239]。24 个月时,平均眼压降低了 2.2 ± 2.5 mmHg vs 3.3 ± 2.9 mmHg,p = 0.333),用药次数减少了 1.1 ± 1.2 vs 1.3 ± 0.1,p 结论:虽然独立和联合 iStent 手术都能在 12 个月内安全降低眼压,但两者的手术成功率在统计学上没有显著差异。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
One-Year comparative analysis between standalone iStent implantation versus combined iStent implantation with phacoemulsification.

Purpose: To evaluate the real-world efficacy and safety of iStent implanted standalone or combined with phacoemulsification in open-angle glaucoma (OAG) patients.

Methods: This is a retrospective observational study of OAG patients who underwent standalone or combined iStent procedures were reviewed. Inclusion criteria included age over 18 years and open angle on gonioscopy. Exclusion criteria were prior incisional glaucoma surgeries, missing data, or follow-up shorter than 6 months. The primary outcome was surgical success between the two groups after one year. Secondary outcomes included differences in IOP reduction and medication use.

Results: We included 48 eyes with primary (n = 44) and secondary OAG (n = 4). Nineteen eyes had standalone while 29 eyes had combined procedures. Kaplan-Meier analysis revealed overall surgical success in 31.3% of eyes after one year. Qualified success was higher in the combined group than the standalone group [62.5% (10 eyes) vs 27.3% (3 eyes), p = 0.239]. At 24 months, mean IOP reduced by 2.2 ± 2.5 mmHg vs 3.3 ± 2.9 mmHg, p = 0.333), and the number of medications reduced by 1.1 ± 1.2 vs 1.3 ± 0.1, p < 0.001) in the standalone and combined group, respectively. Stent occlusion occurred in two eyes.

Conclusions: While both standalone and combined iStent procedures provide safe IOP reduction throughout 12 months, there was no statistically significant difference in surgical success between them.

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来源期刊
CiteScore
3.60
自引率
0.00%
发文量
372
审稿时长
3-8 weeks
期刊介绍: The European Journal of Ophthalmology was founded in 1991 and is issued in print bi-monthly. It publishes only peer-reviewed original research reporting clinical observations and laboratory investigations with clinical relevance focusing on new diagnostic and surgical techniques, instrument and therapy updates, results of clinical trials and research findings.
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