大麻素在促进癌症治疗中的作用:来自循证医学的启示。

IF 4.7 2区 医学 Q1 ONCOLOGY
Current Oncology Reports Pub Date : 2024-11-01 Epub Date: 2024-08-07 DOI:10.1007/s11912-024-01589-4
Magdalena Skórzewska, Katarzyna Gęca
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引用次数: 0

摘要

审查目的:在肿瘤学飞速发展、人们对大麻的看法不断变化的时代,本文件对大麻素在癌症治疗中的作用进行了批判性研究。它追溯了大麻在医疗用途中的历史背景,回顾了大麻从被广泛接受到随后被定罪,再到在现代治疗应用中重新崛起的历程,特别是在循证医学(EBM)的框架内:本研究以循证医学原则为基础,综合了临床试验、系统综述和荟萃分析中的最新研究成果,以评估大麻素在肿瘤学中的疗效和安全性。研究重点是大麻素的缓和作用,同时考虑到疗效、风险评估的细微差别,以及将这些研究成果转化为临床指南所固有的挑战。该研究旨在弥合科学研究与临床实践之间的差距,为未来涉及大麻素的肿瘤疗法和症状管理策略提供真知灼见。该研究评估了在癌症治疗中使用大麻素的潜在益处和风险,以指导临床医生和研究人员制定全面、循证的患者护理方法。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

The Role of Cannabinoids in Advancing Cancer Treatment: Insights from Evidence-Based Medicine.

The Role of Cannabinoids in Advancing Cancer Treatment: Insights from Evidence-Based Medicine.

Purpose of review: This document critically examines the role of cannabinoids in cancer care during an era marked by rapid advancements in oncology and changing perceptions on cannabis. It traces the historical context of cannabis in medicinal use, navigating its journey from widespread acceptance, subsequent criminalization, to its resurgence in modern therapeutic applications, particularly within the framework of Evidence-Based Medicine (EBM).

Recent findings: Anchored in EBM principles, this study synthesizes current research from clinical trials, systematic reviews, and meta-analyses to evaluate the efficacy and safety of cannabinoids in oncology. The focus is on their palliative effects, considering the nuances of effectiveness, risk assessment, and challenges inherent in translating these findings into clinical guidelines. The study seeks to bridge the gap between scientific research and clinical practice, offering insights to inform future oncological therapies and symptom management strategies involving cannabinoids. The potential benefits and risks of cannabinoid use in cancer treatment are assessed to guide clinicians and researchers in developing comprehensive, evidence-based approaches to patient care.

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来源期刊
CiteScore
8.50
自引率
0.00%
发文量
187
审稿时长
6-12 weeks
期刊介绍: This journal aims to review the most important, recently published clinical findings in the field of oncology. By providing clear, insightful, balanced contributions by international experts, the journal intends to serve all those involved in the care of those affected by cancer. We accomplish this aim by appointing international authorities to serve as Section Editors in key subject areas, such as cancer prevention, leukemia, melanoma, neuro-oncology, and palliative medicine. Section Editors, in turn, select topics for which leading experts contribute comprehensive review articles that emphasize new developments and recently published papers of major importance, highlighted by annotated reference lists. An international Editorial Board reviews the annual table of contents, suggests articles of special interest to their country/region, and ensures that topics are current and include emerging research. Commentaries from well-known figures in the field are also provided.
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