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乳酸盐促进 DNA 修复

IF 72.5 1区 医学 Q1 ONCOLOGY
Nature Reviews Cancer Pub Date : 2024-08-05 DOI:10.1038/s41568-024-00732-4
Daniela Senft
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引用次数: 0

摘要

最近发表在《自然》杂志上的一项研究发现，乳酸盐通过促进 DNA 修复蛋白的乳化作用，成为增强胃癌 DNA 修复机制的关键因素，从而导致化疗耐药性。
本文章由计算机程序翻译，如有差异，请以英文原文为准。

Lactate promotes DNA repair

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Lactate promotes DNA repair
In a recent study published in Nature, lactate has been identified as a key player in enhancing DNA repair mechanisms in gastric cancer by promoting lactylation of DNA repair proteins, leading to chemotherapy resistance.
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来源期刊
Nature Reviews Cancer
Nature Reviews Cancer 医学-肿瘤学
CiteScore
111.90
自引率
0.40%
发文量
97
审稿时长
6-12 weeks
期刊介绍： Nature Reviews Cancer, a part of the Nature Reviews portfolio of journals, aims to be the premier source of reviews and commentaries for the scientific communities it serves. The correct abbreviation for abstracting and indexing purposes is Nat. Rev. Cancer. The international standard serial numbers (ISSN) for Nature Reviews Cancer are 1474-175X (print) and 1474-1768 (online). Unlike other journals, Nature Reviews Cancer does not have an external editorial board. Instead, all editorial decisions are made by a team of full-time professional editors who are PhD-level scientists. The journal publishes Research Highlights, Comments, Reviews, and Perspectives relevant to cancer researchers, ensuring that the articles reach the widest possible audience due to their broad scope.
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