局部抗青光眼药物对睑板腺的影响：系统回顾和荟萃分析。

IF 5.9 1区医学 Q1 OPHTHALMOLOGY

Ocular Surface Pub Date : 2024-08-05 DOI:10.1016/j.jtos.2024.07.011

Bruna Grici Cascaldi , Antero Pinto Cardoso Filho , Gustavo Viani Arruda , Eduardo Melani Rocha , Jayter Silva Paula

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引用次数: 0

摘要

睑板腺（MG）功能障碍和青光眼是非常普遍的眼部疾病，严重影响患者的生活质量。越来越多的临床和实验研究报告称，使用局部眼药水降低眼压与睑板腺功能障碍的发生或加重之间存在关联。有关青光眼滴眼液对 MG 诊断参数影响的研究结果各不相同，尤其是在 MG 的形态和功能以及泪膜不稳定性方面。在此，我们通过系统综述和荟萃分析，证实了使用抗青光眼眼药水治疗的患者与MG相关的形态和功能变量发生了较大变化。

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Topical anti-glaucoma medications effects on meibomian glands: Systematic review and meta-analysis

Meibomian gland (MG) dysfunction and glaucoma are very prevalent ocular conditions that significantly impact patients’ quality of life. A growing number of clinical and experimental studies have reported an association between the use of topical eye drops to reduce intraocular pressure and the development or exacerbation of MG dysfunction. Studies investigating the impact of glaucoma eyedrops on MG diagnostic parameters have shown variable results, particularly regarding the morphology and function of MG and tear film instability. Herein, we corroborated the findings of greater changes in morphological and functional variables related to MG in patients treated with antiglaucoma eye drops through a systematic review and meta-analysis.

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来源期刊

Ocular Surface 医学-眼科学

CiteScore

11.60

自引率

14.10%

发文量

审稿时长

39 days

期刊介绍： The Ocular Surface, a quarterly, a peer-reviewed journal, is an authoritative resource that integrates and interprets major findings in diverse fields related to the ocular surface, including ophthalmology, optometry, genetics, molecular biology, pharmacology, immunology, infectious disease, and epidemiology. Its critical review articles cover the most current knowledge on medical and surgical management of ocular surface pathology, new understandings of ocular surface physiology, the meaning of recent discoveries on how the ocular surface responds to injury and disease, and updates on drug and device development. The journal also publishes select original research reports and articles describing cutting-edge techniques and technology in the field. Benefits to authors We also provide many author benefits, such as free PDFs, a liberal copyright policy, special discounts on Elsevier publications and much more. Please click here for more information on our author services. Please see our Guide for Authors for information on article submission. If you require any further information or help, please visit our Support Center