三维打印固有的核磁共振成像可视配件,辅助核磁共振成像引导下的活组织检查。

IF 3.2 Q1 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING
Yanlu Wang
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引用次数: 0

摘要

背景:三维打印机在快速原型制作方面已占据重要地位,在制作尺寸精确、在磁共振成像(MRI)环境中安全且在磁共振成像扫描中可见的物体方面也很可行。使用 3D 打印技术制作磁共振成像可见物体时面临的一个挑战是,硬塑料在标准磁共振成像扫描中是不可见的,而液体则不然。因此,通常会打印出一个空心物体,并在其中填充在核磁共振扫描中可见的液体。然而,这给工程设计带来了挑战,因为使用传统熔融沉积建模(FDM)3D 打印技术制作的物体很容易发生泄漏。数字光处理(DLP)是一种相对现代且经济实惠的三维打印技术,它使用紫外线硬化树脂,能够打印出本质上不漏液的物体。在使用 DLP 打印机打印空心部件时,通常需要在打印过程中添加排水孔,以便未固化的液体树脂逸出。如果不这样做,液态树脂就会残留在物体内部,而在我们的应用中,这正是我们想要的结果。目的:我们设计了一种方法,利用 DLP 技术生产出一种固有的核磁共振成像可视配件,其尺寸公差小,便于进行核磁共振成像引导下的乳腺活检:方法:在不增加排水孔的情况下将物体掏空,并调整打印参数(如z-提升距离),通过表面张力将尽可能多的未固化液体树脂保留在物体内部,这样就可以制作出在核磁共振扫描中固有可见的物体,而无需进一步的后处理:通过我们的方法制造出的物体再造简单、成本低廉、制造步骤最少,而且尺寸精确,在核磁共振成像中清晰可见,无需进一步处理即可直接用于各种应用:我们提出的制造物体的方法本质上既符合核磁共振成像安全要求,又能在核磁共振成像中清晰可见。结论:我们提出的方法既能制造出磁共振成像安全的物体,又能制造出磁共振成像可见的物体。我们提出的工艺非常简单,除 DLP 3D 打印机外,无需其他材料和工具。只需一套廉价的 DLP 3D 打印机套件和医院中的基本清洁和卫生材料,我们就能成功制作出包含精细结构的物体,其空间公差小,可用于核磁共振成像引导下的乳腺活检,从而证明了我们的工艺的可行性。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
3D-printing inherently MRI-visible accessories in aiding MRI-guided biopsies.

Background: 3D printers have gained prominence in rapid prototyping and viable in creating dimensionally accurate objects that are both safe within a Magnetic Resonance Imaging (MRI) environment and visible in MRI scans. A challenge when making MRI-visible objects using 3D printing is that hard plastics are invisible in standard MRI scans, while fluids are not. So typically, a hollow object will be printed and filled with a liquid that will be visible in MRI scans. This poses an engineering challenge however since objects created using traditional Fused Deposition Modeling (FDM) 3D-printing techniques are prone to leakage. Digital Light Processing (DLP) is a relatively modern and affordable 3D-printing technique using UV-hardened resin, capable of creating objects that are inherently liquid-tight. When printing hollow parts using DLP printers, one typically requires adding drainage holes for uncured liquid resin to escape during the printing process. If this is not done liquid resin will remain inside the object, which in our application is the desired outcome.

Purpose: We devised a method to produce an inherently MRI-visible accessory using DLP technology with low dimensional tolerance to facilitate MRI-guided breast biopsies.

Methods: By hollowing out the object without adding drainage holes and tuning printing parameters such as z-lift distance to retain as much uncured liquid resin inside as possible through surface tension, objects that are inherently visible in MRI scans can be created without further post-processing treatment.

Results: Objects created through our method are simple and inexpensive to recreate, have minimal manufacturing steps, and are shown to be dimensionally exact and inherently MRI visible to be directly used in various applications without further treatment.

Conclusion: Our proposed method of manufacturing objects that are inherently both MRI safe, and MRI visible. The proposed process is simple and does not require additional materials and tools beyond a DLP 3D-printer. With only an inexpensive DLP 3D-printer kit and basic cleaning and sanitation materials found in the hospital, we have demonstrated the viability of our process by successfully creating an object containing fine structures with low spatial tolerances used for MRI-guided breast biopsies.

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