Lee Azolai, Valentina Pennacchietti, Matthias Schulz, Henry W S Schroeder, Petr Vacek, Shlomi Constantini, Lidor Bitan, Jonathan Roth, Ulrich-Wilhelm Thomale
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Collected data included indications for using sETV, hydrocephalic history, surgical technique, outcomes, and complications.</p><p><strong>Results: </strong>Sixty-seven cases were included. Forty had a primary sETV, and 27 had a secondary sETV (following a prior shunt, ETV, or both). The average age during surgery was 22 years. Main indications for sETV included an adjacent tumor (n = 15), thick or redundant tuber cinereum (n = 24), and prior ETV failure (n = 16). Fifty-nine patients (88%) had a successful sETV. Eight patients failed 11 ± 8 months following surgery. Reasons for failure included obstruction of the stent, reabsorption insufficiency, and CSF leak (n = 2 each), and massive hygroma and tumor spread (n = 1 each). Complications included subdural hygroma (n = 4), CSF leak (n = 2), and stent malposition (n = 1). There were no complications associated with two stent removals.</p><p><strong>Conclusion: </strong>Stented ETV appears to be feasible and safe. It may be indicated in selected cases such as patients with prior ETV failure, or as a primary treatment in cases with anatomical alterations caused by tumors or thickened tuber cinereum. Future investigations are needed to further elucidate its role in non-communicating hydrocephalus.</p>","PeriodicalId":9970,"journal":{"name":"Child's Nervous System","volume":null,"pages":null},"PeriodicalIF":1.3000,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11511752/pdf/","citationCount":"0","resultStr":"{\"title\":\"Stented endoscopic third ventriculostomy: technique, safety, and indications-a multicenter multinational study.\",\"authors\":\"Lee Azolai, Valentina Pennacchietti, Matthias Schulz, Henry W S Schroeder, Petr Vacek, Shlomi Constantini, Lidor Bitan, Jonathan Roth, Ulrich-Wilhelm Thomale\",\"doi\":\"10.1007/s00381-024-06566-7\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Purpose: </strong>Endoscopic third ventriculostomy (ETV) is an effective treatment for obstructive hydrocephalus. 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引用次数: 0
摘要
目的:内镜下第三脑室造口术(ETV)是治疗梗阻性脑积水的有效方法。继发性造口关闭可能危及生命,也是 ETV 晚期失败的最常见原因,主要是继发于局部瘢痕。旨在保持通畅的局部支架很少使用。在本研究中,我们总结了使用支架 ETV(sETV)的经验、疗效和安全性:资料和方法:我们从四个中心所有连续接受 ETV 支架植入术的患者中回顾性收集了数据。收集的数据包括使用 sETV 的适应症、脑积水病史、手术技术、结果和并发症:结果:共纳入 67 例病例。结果:共纳入 67 例病例,其中 40 例为原发性 sETV,27 例为继发性 sETV(继之前的分流术、ETV 或两者之后)。手术期间的平均年龄为 22 岁。sETV的主要适应症包括邻近肿瘤(15例)、粗大或多余的结节(24例)以及之前的ETV失败(16例)。59名患者(88%)成功进行了sETV。八名患者在术后 11 ± 8 个月失败。失败原因包括支架阻塞、再吸收不足和 CSF 漏(各 2 例),以及大面积瘤疱和肿瘤扩散(各 1 例)。并发症包括硬膜下血肿(4 例)、脑脊液漏(2 例)和支架错位(1 例)。两次支架取出均未出现并发症:结论:支架 ETV 似乎可行且安全。结论:支架 ETV 似乎可行且安全,可用于某些特定病例,如 ETV 之前失败的患者,或作为肿瘤或增厚结节导致解剖结构改变的病例的主要治疗方法。未来还需要进行研究,以进一步阐明其在非交流性脑积水中的作用。
Stented endoscopic third ventriculostomy: technique, safety, and indications-a multicenter multinational study.
Purpose: Endoscopic third ventriculostomy (ETV) is an effective treatment for obstructive hydrocephalus. Secondary stoma closure may be life threatening and is the most common reason for late ETV failure, mostly secondary to local scarring. Local stents intended to maintain patency are rarely used. In this study, we summarize our experience using stented ETV (sETV), efficacy, and safety.
Material and methods: Data was retrospectively collected from all consecutive patients who underwent ETV with stenting at four centers. Collected data included indications for using sETV, hydrocephalic history, surgical technique, outcomes, and complications.
Results: Sixty-seven cases were included. Forty had a primary sETV, and 27 had a secondary sETV (following a prior shunt, ETV, or both). The average age during surgery was 22 years. Main indications for sETV included an adjacent tumor (n = 15), thick or redundant tuber cinereum (n = 24), and prior ETV failure (n = 16). Fifty-nine patients (88%) had a successful sETV. Eight patients failed 11 ± 8 months following surgery. Reasons for failure included obstruction of the stent, reabsorption insufficiency, and CSF leak (n = 2 each), and massive hygroma and tumor spread (n = 1 each). Complications included subdural hygroma (n = 4), CSF leak (n = 2), and stent malposition (n = 1). There were no complications associated with two stent removals.
Conclusion: Stented ETV appears to be feasible and safe. It may be indicated in selected cases such as patients with prior ETV failure, or as a primary treatment in cases with anatomical alterations caused by tumors or thickened tuber cinereum. Future investigations are needed to further elucidate its role in non-communicating hydrocephalus.
期刊介绍:
The journal has been expanded to encompass all aspects of pediatric neurosciences concerning the developmental and acquired abnormalities of the nervous system and its coverings, functional disorders, epilepsy, spasticity, basic and clinical neuro-oncology, rehabilitation and trauma. Global pediatric neurosurgery is an additional field of interest that will be considered for publication in the journal.