仰卧位和非仰卧位睡眠呼吸暂停事件:倒刺咽成形术治疗哪种效果更好?

IF 2.1 4区 医学 Q3 CLINICAL NEUROLOGY
Antonio Moffa, Lucrezia Giorgi, Domiziana Nardelli, Francesco Iafrati, Giannicola Iannella, Rodolfo Lugo, Peter M Baptista, Manuele Casale
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引用次数: 0

摘要

目的在阻塞性睡眠呼吸暂停(OSA)的治疗方案中,咽内手术经历了重大变革,并获得了坚实的科学支持。然而,确定最佳候选者至关重要。本研究旨在介绍本诊所采用改良Alianza技术的结果,以显示手术对中度重度OSA患者仰卧位和非仰卧位呼吸暂停水平的影响差异。方法回顾性入选受中度重度OSA(呼吸暂停-高通气指数(AHI)为15)影响、有环形腭塌的成人患者,以及改良Alianza技术的候选者。每位受试者都在术前和术后进行了多导睡眠图检查,并在至少六个月后进行了随访检查。我们发现术后仰卧位和非仰卧位 AHI 均有明显下降。与仰卧位 AHI(从 42.51 降至 25.93,p = 0.0003)相比,非仰卧位 AHI 的下降幅度更大(从 20.89 降至 11.64 次/小时,p = 0.0001)。随后,我们根据患者术前是否受体位性 OSA 影响将其分为两组。术前有体位性 OSA 的患者术后非仰卧位 AHI 下降的百分比低于仰卧位 AHI 下降的百分比,但这一差异没有统计学意义。相反,与仰卧位 AHI 相比,非体位患者组的非仰卧位 AHI 下降率更高,但差异无统计学意义。与仰卧位呼吸暂停相比,非仰卧位呼吸暂停患者对手术的反应更佳。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

Supine or non-supine sleep apnea events: which can be treated better with Barbed Pharyngoplasty?

Supine or non-supine sleep apnea events: which can be treated better with Barbed Pharyngoplasty?

Purpose

Among the treatment options for Obstructive Sleep Apnea (OSA), intrapharyngeal surgery has undergone significant changes and received solid scientific support. However, it is crucial to identify the best candidate. This study aims to present the results of the modified Alianza technique in our clinic to show the differences in the impact of surgery on supine and non-supine apnea levels in moderate-severe OSA patients.

Methods

Adult patients affected by moderate-severe OSA (Apnea-Hypopnea Index (AHI) > 15), having circular palatal collapse, and candidates for modified Alianza Tecnique were retrospectively enrolled. Each subject performed polysomnography pre- and post-operatively, and the follow-up check was performed after at least six months.

Results

This study enrolled 24 patients who underwent the Modified Alianza technique for sleep apnea. We found significant reductions in both supine and non-supine AH) after surgery. Non-supine AHI showed a greater reduction (from 20.89 to 11.64 episodes/hour, p = 0.0001) than supine AHI (from 42.51 to 25.93, p = 0.0003). We subsequently divided the patients into two groups based on whether they were affected by positional OSA before surgery. There was a lower percentage decrease in non-supine AHI compared to supine AHI after surgery in patients who were positional before surgery, but this difference was not statistically significant. Conversely, in the non-positional patient group, there was a higher decrease in non-supine AHI compared to supine AHI, although this was not statistically significant.

Conclusion

The Modified Alianza Tecnique leads to notable enhancement in AHI among patients with OSA. Non-supine apneas exhibit a more favorable response to the surgery than supine apneas.

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来源期刊
Sleep and Breathing
Sleep and Breathing 医学-呼吸系统
CiteScore
5.20
自引率
4.00%
发文量
222
审稿时长
3-8 weeks
期刊介绍: The journal Sleep and Breathing aims to reflect the state of the art in the international science and practice of sleep medicine. The journal is based on the recognition that management of sleep disorders requires a multi-disciplinary approach and diverse perspectives. The initial focus of Sleep and Breathing is on timely and original studies that collect, intervene, or otherwise inform all clinicians and scientists in medicine, dentistry and oral surgery, otolaryngology, and epidemiology on the management of the upper airway during sleep. Furthermore, Sleep and Breathing endeavors to bring readers cutting edge information about all evolving aspects of common sleep disorders or disruptions, such as insomnia and shift work. The journal includes not only patient studies, but also studies that emphasize the principles of physiology and pathophysiology or illustrate potentially novel approaches to diagnosis and treatment. In addition, the journal features articles that describe patient-oriented and cost-benefit health outcomes research. Thus, with peer review by an international Editorial Board and prompt English-language publication, Sleep and Breathing provides rapid dissemination of clinical and clinically related scientific information. But it also does more: it is dedicated to making the most important developments in sleep disordered breathing easily accessible to clinicians who are treating sleep apnea by presenting well-chosen, well-written, and highly organized information that is useful for patient care.
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