4- 烷炔化吡唑-3-酮的应用：吡唑-4-基呋喃和/或噻吩-2-羧酸盐的合成

IF 1.8 3区化学 Q3 CHEMISTRY, ORGANIC

Synthetic Communications Pub Date : 2024-08-17 DOI:10.1080/00397911.2024.2385539

Takafumi Fujita , Fumi Okabe-Nakahara , Hiroshi Maruoka , Eiichi Masumoto

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引用次数: 0

摘要

介绍了 4-炔基吡唑-3-酮的化学反应性和应用。通过环三烯丙基化反应，可以方便地合成新型吡唑-4-基呋喃和/或噻吩-2-羧酸盐。

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Applications of 4-alkynylated pyrazol-3-ones: Synthesis of pyrazol-4-yl furan- and/or thiophene-2-carboxylates

Chemical reactivity and applications of 4-alkynylated pyrazol-3-ones are described. A facile access to the synthesis of novel pyrazol-4-yl furan- and/or thiophene-2-carboxylates through the ring transformation and subsequent acylation of 4-alkynylated pyrazol-3-ones as the key intermediates, which were prepared from pyrazole-4,5-dione and terminal alkynes, in moderate to good yields is achieved. All the synthesized compounds were characterized by spectroscopic analysis.

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来源期刊

Synthetic Communications 化学-有机化学

CiteScore

4.40

自引率

4.80%

发文量

156

审稿时长

4.3 months

期刊介绍： Synthetic Communications presents communications describing new methods, reagents, and other synthetic work pertaining to organic chemistry with sufficient experimental detail to permit reported reactions to be repeated by a chemist reasonably skilled in the art. In addition, the Journal features short, focused review articles discussing topics within its remit of synthetic organic chemistry.