{"title":"使用低浓度氧化亚氮气体麻醉进行玻璃体气体置换玻璃体切除术的眼压和安全性","authors":"Santaro Noguchi, Shunsuke Nakakura, Asuka Noguchi, Hitoshi Tabuchi","doi":"10.1097/IAE.0000000000004225","DOIUrl":null,"url":null,"abstract":"<p><strong>Purpose: </strong>The aim of this study is to evaluate the efficacy and safety of vitrectomy with vitreous gas replacement using low-concentration nitrous oxide (N 2 O) gas anesthesia, focusing on intraocular pressure (IOP) changes, pain, anxiety, and safety outcomes.</p><p><strong>Methods: </strong>This retrospective study analyzed 133 patients undergoing fluid-air exchange without use of SF6 or C3F8, at Saneikai Tsukazaki Hospital, Japan, from April 2019 to March 2022. Participants were divided into two groups: those receiving low-concentration nitrous oxide gas anesthesia (N 2 O group) and those receiving local anesthesia with room air inhalation (air group). IOP, pain, anxiety levels, and intraoperative complications were assessed.</p><p><strong>Results: </strong>No significant differences were found in IOP changes postoperatively between the N 2 O and air groups. The N 2 O group reported significantly lower pain scores and had lower intraoperative systolic blood pressure and heart rate changes compared with the air group. No significant intraoperative or postoperative complications were observed in either group.</p><p><strong>Conclusion: </strong>Vitrectomy with fluid-air exchange using low-concentration nitrous oxide gas anesthesia is safe, does not increase IOP, and may offer benefits in reducing intraoperative pain and stabilizing vital signs compared with traditional local anesthesia methods. This approach could be considered a viable option for vitreous surgery requiring fluid-air exchange.</p>","PeriodicalId":54486,"journal":{"name":"Retina-The Journal of Retinal and Vitreous Diseases","volume":" ","pages":"2154-2159"},"PeriodicalIF":2.3000,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"INTRAOCULAR PRESSURE AND SAFETY OF VITRECTOMY WITH VITREOUS GAS REPLACEMENT USING LOW-CONCENTRATION NITROUS OXIDE GAS ANESTHESIA.\",\"authors\":\"Santaro Noguchi, Shunsuke Nakakura, Asuka Noguchi, Hitoshi Tabuchi\",\"doi\":\"10.1097/IAE.0000000000004225\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Purpose: </strong>The aim of this study is to evaluate the efficacy and safety of vitrectomy with vitreous gas replacement using low-concentration nitrous oxide (N 2 O) gas anesthesia, focusing on intraocular pressure (IOP) changes, pain, anxiety, and safety outcomes.</p><p><strong>Methods: </strong>This retrospective study analyzed 133 patients undergoing fluid-air exchange without use of SF6 or C3F8, at Saneikai Tsukazaki Hospital, Japan, from April 2019 to March 2022. Participants were divided into two groups: those receiving low-concentration nitrous oxide gas anesthesia (N 2 O group) and those receiving local anesthesia with room air inhalation (air group). IOP, pain, anxiety levels, and intraoperative complications were assessed.</p><p><strong>Results: </strong>No significant differences were found in IOP changes postoperatively between the N 2 O and air groups. The N 2 O group reported significantly lower pain scores and had lower intraoperative systolic blood pressure and heart rate changes compared with the air group. No significant intraoperative or postoperative complications were observed in either group.</p><p><strong>Conclusion: </strong>Vitrectomy with fluid-air exchange using low-concentration nitrous oxide gas anesthesia is safe, does not increase IOP, and may offer benefits in reducing intraoperative pain and stabilizing vital signs compared with traditional local anesthesia methods. This approach could be considered a viable option for vitreous surgery requiring fluid-air exchange.</p>\",\"PeriodicalId\":54486,\"journal\":{\"name\":\"Retina-The Journal of Retinal and Vitreous Diseases\",\"volume\":\" \",\"pages\":\"2154-2159\"},\"PeriodicalIF\":2.3000,\"publicationDate\":\"2024-12-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Retina-The Journal of Retinal and Vitreous Diseases\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1097/IAE.0000000000004225\",\"RegionNum\":2,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"OPHTHALMOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Retina-The Journal of Retinal and Vitreous Diseases","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1097/IAE.0000000000004225","RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"OPHTHALMOLOGY","Score":null,"Total":0}
INTRAOCULAR PRESSURE AND SAFETY OF VITRECTOMY WITH VITREOUS GAS REPLACEMENT USING LOW-CONCENTRATION NITROUS OXIDE GAS ANESTHESIA.
Purpose: The aim of this study is to evaluate the efficacy and safety of vitrectomy with vitreous gas replacement using low-concentration nitrous oxide (N 2 O) gas anesthesia, focusing on intraocular pressure (IOP) changes, pain, anxiety, and safety outcomes.
Methods: This retrospective study analyzed 133 patients undergoing fluid-air exchange without use of SF6 or C3F8, at Saneikai Tsukazaki Hospital, Japan, from April 2019 to March 2022. Participants were divided into two groups: those receiving low-concentration nitrous oxide gas anesthesia (N 2 O group) and those receiving local anesthesia with room air inhalation (air group). IOP, pain, anxiety levels, and intraoperative complications were assessed.
Results: No significant differences were found in IOP changes postoperatively between the N 2 O and air groups. The N 2 O group reported significantly lower pain scores and had lower intraoperative systolic blood pressure and heart rate changes compared with the air group. No significant intraoperative or postoperative complications were observed in either group.
Conclusion: Vitrectomy with fluid-air exchange using low-concentration nitrous oxide gas anesthesia is safe, does not increase IOP, and may offer benefits in reducing intraoperative pain and stabilizing vital signs compared with traditional local anesthesia methods. This approach could be considered a viable option for vitreous surgery requiring fluid-air exchange.
期刊介绍:
RETINA® focuses exclusively on the growing specialty of vitreoretinal disorders. The Journal provides current information on diagnostic and therapeutic techniques. Its highly specialized and informative, peer-reviewed articles are easily applicable to clinical practice.
In addition to regular reports from clinical and basic science investigators, RETINA® publishes special features including periodic review articles on pertinent topics, special articles dealing with surgical and other therapeutic techniques, and abstract cards. Issues are abundantly illustrated in vivid full color.
Published 12 times per year, RETINA® is truly a “must have” publication for anyone connected to this field.