美国变性和非二元青年对长效注射剂暴露前预防的看法和偏好。

IF 2.6 2区 医学 Q2 INFORMATION SCIENCE & LIBRARY SCIENCE
Allegra R Gordon, Samantha Haiken, Gabriel R Murchison, Madina Agénor, Jaclyn M W Hughto, Kimberly M Nelson
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引用次数: 0

摘要

用于预防艾滋病的长效注射接触前预防疗法(LAI-PrEP)于 2021 年获准在美国使用,但变性和非二元青年对 LAI-PrEP 的看法却知之甚少,而这一群体在预防艾滋病方面面临着巨大的障碍。我们调查了美国变性和非二元青年对 LAI-PrEP 的看法和态度,以及 LAI-PrEP 的优势和劣势与 PrEP 持续护理的关系。我们对 31 名报告使用口服 PrEP 或符合 PrEP 资格的变性和非二元青年进行了半结构化访谈。我们采用演绎式 RADaR 方法对回答进行了分析,以确定与 PrEP 持续护理相关的 LAI-PrEP 感知,并采用归纳式主题分析来探讨关键主题。在这项研究中,所有有 PrEP 经验的参与者和大多数没有 PrEP 经验的参与者都表示对 LAI-PrEP 感兴趣,认为它比每日口服药物更有优势(如更少的依从性挑战)。出现了三个关键主题:(1) 一些参与者将 LAI-PrEP 的优势与性别确认护理的经验联系起来(例如,通过使用激素熟悉针头)。(2) 参与者权衡了影响其 LAI-PrEP 偏好的权衡和背景因素(例如,兴趣取决于接受注射的地 点在地理上是否方便)。(3) 参与者设想了其他可提高 LAI-PrEP 可接受性和使用率的方法(如家庭注射)。艾滋病毒预防计划应纳入变性和非二元青年的见解,以确保新出现的艾滋病毒预防技术能够被所有性别模式的人所接受,并对他们的需求和关注做出回应。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Long-Acting Injectable Pre-Exposure Prophylaxis Perceptions and Preferences Among Transgender and Nonbinary Young Adults in the United States.

Long-acting injectable pre-exposure prophylaxis for HIV prevention (LAI-PrEP) was approved for use in the United States in 2021, yet little is known about perceptions of LAI-PrEP among transgender and nonbinary young adults, a group that faces substantial barriers to HIV prevention. We investigated US transgender and nonbinary young adults' perceptions of and attitudes toward LAI-PrEP and how perceived advantages and disadvantages of LAI-PrEP related to the PrEP continuum of care. We conducted semi-structured interviews with 31 transgender and nonbinary young adults who reported oral PrEP use or were PrEP-eligible. We analyzed responses using both a deductive RADaR approach, to identify LAI-PrEP perceptions relevant to the PrEP continuum of care, and an inductive thematic analysis to explore key themes. In this study, all PrEP-experienced and most PrEP-naïve participants indicated an interest in LAI-PrEP, citing advantages over daily oral medication (e.g., fewer adherence challenges). Three key themes emerged: (1) Some participants linked perceived advantages of LAI-PrEP to experiences with gender-affirming care (e.g., familiarity with needles via hormone use). (2) Participants weighed trade-offs and contextual factors that influenced their LAI-PrEP preferences (e.g., interest contingent on whether location for receiving injection was geographically accessible). (3) Participants envisaged alternative delivery methods that could enhance LAI-PrEP acceptability and uptake (e.g., home injection). HIV prevention programs should incorporate the insights of transgender and nonbinary young adults to ensure that emerging HIV prevention technologies are accessible and responsive to the needs and concerns of people of all gender modalities.

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来源期刊
CiteScore
6.80
自引率
6.20%
发文量
109
期刊介绍: QUALITATIVE HEALTH RESEARCH is an international, interdisciplinary, refereed journal for the enhancement of health care and to further the development and understanding of qualitative research methods in health care settings. We welcome manuscripts in the following areas: the description and analysis of the illness experience, health and health-seeking behaviors, the experiences of caregivers, the sociocultural organization of health care, health care policy, and related topics. We also seek critical reviews and commentaries addressing conceptual, theoretical, methodological, and ethical issues pertaining to qualitative enquiry.
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