鞭毛蛋白 FliL：多种多样。

IF 2.6 2区生物学 Q3 BIOCHEMISTRY & MOLECULAR BIOLOGY

Molecular Microbiology Pub Date : 2024-10-01 Epub Date: 2024-08-03 DOI:10.1111/mmi.15301

Jonathan D Partridge, Rasika M Harshey

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引用次数: 0

摘要

FliL 是一种细菌鞭毛蛋白，在多种细菌中与定子复合体结合并调节离子流。FliL 还与其他功能有关，如稳定鞭毛杆、调节转子偏向、感知表面和调节基因表达。一个蛋白质怎么能做这么多事情？要了解它的众多功能，其位置至关重要。这篇综述将探讨相关证据，试图解决一些相互矛盾的发现，并提供有关 FliL 的新思路。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Flagellar protein FliL: A many-splendored thing.

FliL is a bacterial flagellar protein demonstrated to associate with, and regulate ion flow through, the stator complex in a diverse array of bacterial species. FliL is also implicated in additional functions such as stabilizing the flagellar rod, modulating rotor bias, sensing the surface, and regulating gene expression. How can one protein do so many things? Its location is paramount to understanding its numerous functions. This review will look at the evidence, attempt to resolve some conflicting findings, and offer new thoughts on FliL.

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来源期刊

Molecular Microbiology 生物-生化与分子生物学

CiteScore

7.20

自引率

5.60%

发文量

132

审稿时长

1.7 months

期刊介绍： Molecular Microbiology, the leading primary journal in the microbial sciences, publishes molecular studies of Bacteria, Archaea, eukaryotic microorganisms, and their viruses. Research papers should lead to a deeper understanding of the molecular principles underlying basic physiological processes or mechanisms. Appropriate topics include gene expression and regulation, pathogenicity and virulence, physiology and metabolism, synthesis of macromolecules (proteins, nucleic acids, lipids, polysaccharides, etc), cell biology and subcellular organization, membrane biogenesis and function, traffic and transport, cell-cell communication and signalling pathways, evolution and gene transfer. Articles focused on host responses (cellular or immunological) to pathogens or on microbial ecology should be directed to our sister journals Cellular Microbiology and Environmental Microbiology, respectively.