不断发展的 COVID-19 减毒活疫苗。

IF 20.5 1区生物学 Q1 MICROBIOLOGY

Nature Microbiology Pub Date : 2024-08-02 DOI:10.1038/s41564-024-01770-2

Simone Pecetta, Rino Rappuoli

引用次数: 0

摘要

基于引入过早终止密码子的基因方法可以减弱 SARS-CoV-2 并诱导保护性粘膜免疫。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

The evolving landscape of live attenuated COVID-19 vaccines

查看原文本刊更多论文

The evolving landscape of live attenuated COVID-19 vaccines

A genetic approach based on the introduction of premature termination codons can attenuate SARS-CoV-2 and induce protective mucosal immunity.

求助全文

通过发布文献求助，成功后即可免费获取论文全文。去求助

来源期刊

Nature Microbiology Immunology and Microbiology-Microbiology

CiteScore

44.40

自引率

1.10%

发文量

226

期刊介绍： Nature Microbiology aims to cover a comprehensive range of topics related to microorganisms. This includes: Evolution: The journal is interested in exploring the evolutionary aspects of microorganisms. This may include research on their genetic diversity, adaptation, and speciation over time. Physiology and cell biology: Nature Microbiology seeks to understand the functions and characteristics of microorganisms at the cellular and physiological levels. This may involve studying their metabolism, growth patterns, and cellular processes. Interactions: The journal focuses on the interactions microorganisms have with each other, as well as their interactions with hosts or the environment. This encompasses investigations into microbial communities, symbiotic relationships, and microbial responses to different environments. Societal significance: Nature Microbiology recognizes the societal impact of microorganisms and welcomes studies that explore their practical applications. This may include research on microbial diseases, biotechnology, or environmental remediation. In summary, Nature Microbiology is interested in research related to the evolution, physiology and cell biology of microorganisms, their interactions, and their societal relevance.