1990 年至 2019 年全球、地区和国家抑郁症发病率的时间趋势:针对 2019 年 GBD 的年龄段队列分析。

IF 3.6 3区 医学 Q1 PSYCHIATRY
Yuhang Wu, Luying Fan, Fan Xia, Yunzhe Zhou, Haiyan Wang, Lijuan Feng, Shudong Xie, Wendi Xu, Zhiqin Xie, Jing He, Dan Liu, Sui He, Yuting Xu, Jing Deng, Tingting Wang, Lizhang Chen
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引用次数: 0

摘要

背景:即使初级卫生保健取得了进步,抑郁障碍仍然是一个重大的全球公共卫生问题。我们对过去 30 年全球、地区和国家的抑郁障碍发病趋势进行了深入分析:我们从《2019 年全球疾病负担研究》(GBD)中获得了按性别(女性、男性和两者)、地区(204 个国家)、年龄(5-84 岁)、年份(1990-2019 年)划分的抑郁障碍发病率数据。此外,还利用年龄-时期-队列模型估算了1990年至2019年期间的净漂移、本地漂移、年龄、时期和队列效应:与1990年相比,2019年抑郁障碍的发病率增加了59.3%,达到2.9亿人(95% UI:256,328),但年龄标准化发病率下降了2.35%,为每10万人3588.25例(3152.71,4060.42)。发病率正在从中青年人口向老年人口过渡。从 1990 年到 2019 年,发病率的净漂移从社会人口指数(SDI)中低地区的-0.54%(-0.61%,-0.47%)到社会人口指数(SDI)高地区的 0.52%(0.25%,0.79%)不等。在全球范围内,抑郁障碍的发病率随着年龄的增长而增加,时期效应显示风险在下降,而队列效应在 20 世纪 60 年代后开始下降:我们目前的研究结果表明,在年龄、时期和队列这三个维度上,抑郁障碍的发病率在 SDI 地区和国家之间存在着巨大的健康差异,并有可能成为优先考虑的问题。改善抑郁障碍事件进展的医疗保健范围可以扩大到所有年龄段的男性和女性。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Global, regional, and national time trends in incidence for depressive disorders, from 1990 to 2019: an age-period-cohort analysis for the GBD 2019.

Background: Even with advances in primary health care, depressive disorders remain a major global public health problem. We conducted an in-depth analysis of global, regional and national trends in depressive disorders incidence over the past 30 years.

Methods: Data on the incidence of depressive disorders were obtained by sex (female, male, and both), location (204 countries), age (5-84 years), year (1990-2019) from the Global Burden of Disease Study (GBD) 2019. Further, age-period-cohort modeling was used to estimate the net drift, local drift, age, period and cohort effects between 1990 and 2019.

Results: In 2019, although the incidence of depressive disorders has increased by 59.3% to 290 million (95% UI: 256, 328), the age-standardized incidence rate has decreased by 2.35% to 3588.25 per 100,000 people (3152.71, 4060.42) compared to 1990. There was an emerging transition of incidences from the young and middle-aged population to the old population. From 1990 to 2019, the net drift of incidence rate ranged from -0.54% (-0.61%, -0.47%) in low-middle Socio-demographic Index (SDI) regions to 0.52% (0.25%, 0.79%) in high SDI regions. Globally, the incidence rate of depressive disorders increases with age, period effects showing a decreasing risk and cohort effects beginning to decline after the 1960s.

Conclusions: Our current findings reflect substantial health disparities and potential priority-setting of depressive disorders incidence in the three dimensions of age, period and cohort across SDI regions, countries. The scope of healthcare to improve the progression of depressive disorders events can be expanded to include males, females of all ages.

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来源期刊
CiteScore
6.60
自引率
2.70%
发文量
43
审稿时长
>12 weeks
期刊介绍: Annals of General Psychiatry considers manuscripts on all aspects of psychiatry, including neuroscience and psychological medicine. Both basic and clinical neuroscience contributions are encouraged. Annals of General Psychiatry emphasizes a biopsychosocial approach to illness and health and strongly supports and follows the principles of evidence-based medicine. As an open access journal, Annals of General Psychiatry facilitates the worldwide distribution of high quality psychiatry and mental health research. The journal considers submissions on a wide range of topics including, but not limited to, psychopharmacology, forensic psychiatry, psychotic disorders, psychiatric genetics, and mood and anxiety disorders.
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