超重与 COVID-19 结果之间的关联:综述。

IF 8 2区 医学 Q1 ENDOCRINOLOGY & METABOLISM
Obesity Reviews Pub Date : 2024-08-03 DOI:10.1111/obr.13803
Jamie Matu, Alex Griffiths, Oliver M. Shannon, Andrew Jones, Rhiannon Day, Duncan Radley, Alison Feeley, Lisa Mabbs, Jamie Blackshaw, Naveed Sattar, Louisa Ells
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引用次数: 0

摘要

本综述评估了超重与 COVID-19 结果之间的关系。系统检索了MEDLINE、PsycINFO和CINAHL中评估超重与COVID-19结果相关性的综述。根据重症监护室入院、有创机械通气管理、疾病严重程度、住院和死亡率等可用数据进行了二阶荟萃分析。采用 AMSTAR-2 评估工具对纳入的综述进行了质量评估。共纳入了 52 篇系统综述,其中 49 篇包括荟萃分析。严重后果(OR = 1.86;95% CI:1.70 至 2.05)、入住重症监护室(OR = 1.58;95% CI:1.45 至 1.72)、使用有创机械通气(OR = 1.70;95% CI:1.57 至 1.83)、住院(OR = 1.82;95% CI:1.61 至 2.05),以及 COVID-19 感染后的死亡率(OR = 1.35;95% CI:1.24 至 1.48)。在所纳入的综述中,有关种族等调节因素影响的证据有限,且大部分纳入的综述质量较差。肥胖似乎是导致严重 COVID-19 结果(包括死亡)的一个重要的可调节感染前风险因素。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

The association between excess weight and COVID-19 outcomes: An umbrella review

The association between excess weight and COVID-19 outcomes: An umbrella review

This umbrella review assessed the association between excess weight and COVID-19 outcomes. MEDLINE, PsycINFO, and CINAHL were systematically searched for reviews that assessed the association between excess weight and COVID-19 outcomes. A second-order meta-analysis was conducted on the available data for intensive care unit admission, invasive mechanical ventilation administration, disease severity, hospitalization, and mortality. The quality of included reviews was assessed using the AMSTAR-2 appraisal tool. In total, 52 systematic reviews were included, 49 of which included meta-analyses. The risk of severe outcomes (OR = 1.86; 95% CI: 1.70 to 2.05), intensive care unit admission (OR = 1.58; 95% CI: 1.45 to 1.72), invasive mechanical ventilation administration (OR = 1.70; 95% CI: 1.57 to 1.83), hospitalization (OR = 1.82; 95% CI: 1.61 to 2.05), and mortality (OR = 1.35; 95% CI: 1.24 to 1.48) following COVID-19 infection was significantly higher in individuals living with excess weight compared with those with a healthy weight. There was limited evidence available in the included reviews regarding the influence of moderating factors such as ethnicity, and the majority of included reviews were of poor quality. Obesity appears to represent an important modifiable pre-infection risk factor for severe COVID-19 outcomes, including death.

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来源期刊
Obesity Reviews
Obesity Reviews 医学-内分泌学与代谢
CiteScore
19.30
自引率
1.10%
发文量
130
审稿时长
1 months
期刊介绍: Obesity Reviews is a monthly journal publishing reviews on all disciplines related to obesity and its comorbidities. This includes basic and behavioral sciences, clinical treatment and outcomes, epidemiology, prevention and public health. The journal should, therefore, appeal to all professionals with an interest in obesity and its comorbidities. Review types may include systematic narrative reviews, quantitative meta-analyses and narrative reviews but all must offer new insights, critical or novel perspectives that will enhance the state of knowledge in the field. The editorial policy is to publish high quality peer-reviewed manuscripts that provide needed new insight into all aspects of obesity and its related comorbidities while minimizing the period between submission and publication.
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