免疫疗法治疗免疫相关疾病的意外后果：矛盾性银屑病和杜匹单抗相关肌肉骨骼综合征。

IF 3.6 2区医学 Q2 RHEUMATOLOGY

Journal of Rheumatology Pub Date : 2024-10-01 DOI:10.3899/jrheum.2024-0664

Elizabeth B Wallace, Catherine D Hughes, Bina Menon, Bruce Kirkham

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引用次数: 0

摘要

在银屑病和银屑病关节炎研究与评估小组（GRAPPA）2023 年年会上，有两场演讲的重点是银屑病（PsO）免疫调节疗法的意外后果。Elizabeth Wallace 博士介绍了肿瘤坏死因子抑制剂治疗银屑病和其他炎症性疾病的意外后果。这些后果包括自相矛盾的银屑病，其定义是治疗似乎诱发了意想不到的新银屑病病例或银屑病症状恶化。Bruce Kirkham 博士重点讨论了杜匹单抗治疗的意外后果，其中可能包括类似银屑病关节炎的肌肉骨骼综合征。

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Unintended Consequences of Immune Therapy for Immune-Mediated Diseases: Paradoxical Psoriasis and Dupilumab-Associated Musculoskeletal Syndrome.

Two presentations at the Group for Research and Assessment of Psoriasis and Psoriatic Arthritis (GRAPPA) 2023 annual meeting focused on unintended consequences of immunomodulatory therapy for psoriasis (PsO). Dr. Elizabeth Wallace presented on unintended consequences of tumor necrosis factor inhibitors for treating PsO and other inflammatory disorders. These consequences include paradoxical PsO, which is defined as unexpected new PsO cases or worsening PsO symptoms seemingly induced by treatment. Dr. Bruce Kirkham focused on unintended consequences of dupilumab treatment, which can include a musculoskeletal syndrome similar to psoriatic arthritis.

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来源期刊

Journal of Rheumatology 医学-风湿病学

CiteScore

6.50

自引率

5.10%

发文量

285

审稿时长

1 months

期刊介绍： The Journal of Rheumatology is a monthly international serial edited by Earl D. Silverman. The Journal features research articles on clinical subjects from scientists working in rheumatology and related fields, as well as proceedings of meetings as supplements to regular issues. Highlights of our 41 years serving Rheumatology include: groundbreaking and provocative editorials such as "Inverting the Pyramid," renowned Pediatric Rheumatology, proceedings of OMERACT and the Canadian Rheumatology Association, Cochrane Musculoskeletal Reviews, and supplements on emerging therapies.