骨软骨自体移植与同侧距骨外侧自体移植物治疗距骨内侧骨软骨损伤的疗效。

IF 16.4 1区 化学 Q1 CHEMISTRY, MULTIDISCIPLINARY
Accounts of Chemical Research Pub Date : 2024-08-01 Epub Date: 2024-04-25 DOI:10.4055/cios23327
Jae Wan Suh, Joo Han Kwon, Dae Hee Lee, Jae Uk Jung, Hyun-Woo Park
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引用次数: 0

摘要

背景:骨软骨自体移植(OAT骨软骨自体移植(OAT)已被广泛用于治疗距骨骨软骨损伤(OLT)。以往的研究报告显示,使用膝关节髁间凹槽或股骨髁非负重区的骨软骨自体移植取得了成功。然而,在一些病例中也观察到了膝关节供体部位的发病率。本研究旨在探讨同侧距骨关节面自体移植物作为内侧OLT替代供体部位的结果和安全性:在40名接受OAT的患者中,29名患者被排除在外。回顾性分析了2011年至2022年期间接受OAT并从同侧距骨关节面获取骨软骨移植物的11例患者。踝关节磁共振成像测量了OLT的大小,包括冠状长度、矢状长度、深度和面积。临床结果采用美国骨科足踝协会(AOFAS)踝关节-后足量表和视觉模拟量表(VAS)进行评估。术后和术后一年进行踝关节负重X光片检查:术后平均随访时间为 64.7 个月(14-137 个月)。病变的平均直径为 8.8 毫米(范围为 8-9.9 毫米)。病变的平均大小为 51.2 平方毫米(范围为 33.6-71.3 平方毫米),所有病变均包括软骨下囊肿。病变的平均深度为 7.3 毫米(范围为 6.2-9.1 毫米)。所有测定的临床结果在术后都有所改善,包括 AOFAS 评分(术前,55.4 ± 9.0;1 年随访,92.1 ± 7.6;P = 0.001)和 VAS 评分(术前,5.5 ± 0.7;1 年随访,1.9 ± 0.8;P = 0.001)。术后1年,移植物和供体部位的所有踝关节负重X光片均未显示踝关节关节炎改变、外侧距骨穹隆塌陷、移植物部位延迟结合或不结合:对于单个内侧OLT而言,从同侧距骨外侧关节面采集自体移植物不会造成膝关节供体部位的病变,是OAT进行OLT的良好替代方法。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Outcomes of Osteochondral Autologous Transplantation with Ipsilateral Lateral Talar Autograft for Medial Osteochondral Lesions of the Talus.

Background: Osteochondral autologous transplantation (OAT) has been widely used in the treatment of osteochondral lesion of the talus (OLT). Previous studies have reported successful outcomes following the use of osteochondral autogenous grafts from the intercondylar notch of the knee or a non-weight-bearing region of the femoral condyle. However, donor-site morbidity of the knee joint has been observed in several cases. This study aimed to investigate the outcomes and safety of OAT with autografts from the ipsilateral lateral talar articular facet as an alternative donor site for medial OLT.

Methods: Among 40 patients who underwent OAT, 29 patients were excluded. Eleven patients who underwent OAT with an osteochondral graft harvested from the ipsilateral lateral talar articular facet from 2011 to 2022 were retrospectively analyzed. The size of OLT was measured on ankle magnetic resonance imaging, including coronal length, sagittal length, depth, and area. Clinical outcomes were evaluated using the American Orthopaedic Foot and Ankle Society (AOFAS) ankle-hindfoot scale and a visual analog scale (VAS). Weight-bearing ankle radiographs were obtained postoperatively and at 1 year after surgery.

Results: The average follow-up time after surgery was 64.7 months (range, 14-137 months). The average diameter of lesions was 8.8 mm (range, 8-9.9 mm). The average size of lesions was 51.2 mm2 (range, 33.6-71.3 mm2) , and all lesions included subchondral cysts. The average depth of lesions was 7.3 mm (range, 6.2-9.1 mm). Graft sizes ranged from 8 to 10 mm in diameter (8 mm, n = 1; 10 mm, n = 10) All measured clinical outcomes improved postoperatively, including the AOFAS scores (preoperative, 55.4 ± 9.0; 1-year follow-up, 92.1 ± 7.6; p = 0.001) and VAS scores (preoperative, 5.5 ± 0.7; 1-year follow-up, 1.9 ± 0.8; p = 0.001). All weight-bearing ankle radiographs of the graft and donor sites did not reveal arthritic change in the ankle joint, lateral talar dome collapse, and graft-site delayed union or nonunion at 1 year after surgery.

Conclusions: For a single medial OLT, harvesting autografts from the ipsilateral lateral talar articular facet without knee donor-site morbidities can be a good alternative in OAT for OLT.

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来源期刊
Accounts of Chemical Research
Accounts of Chemical Research 化学-化学综合
CiteScore
31.40
自引率
1.10%
发文量
312
审稿时长
2 months
期刊介绍: Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.
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