十字韧带固定和后稳定全膝关节置换术的载荷相关特性:生物力学研究

IF 16.4 1区 化学 Q1 CHEMISTRY, MULTIDISCIPLINARY
Accounts of Chemical Research Pub Date : 2024-08-01 Epub Date: 2024-07-12 DOI:10.4055/cios23356
Jason H Lee, Ran Schwarzkopf, Genevieve Fraipont, Ghita Bouzarif, Michelle H McGarry, Thay Q Lee
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引用次数: 0

摘要

背景:髌骨股关节和胫骨股关节的负重增加与全膝关节置换术(TKA)并发症有关。因此,本研究旨在量化髌股关节和胫股关节的生物力学特征,并模拟后交叉韧带保留(CR)和后稳定(PS)TKA 后的不同负重需求:使用具有肌肉加载功能的定制膝关节系统对八个新鲜冷冻的尸体膝关节(平均年龄 68.4 岁;范围 40-86 岁)进行了测试。先用CR后用PS TKA假体对TKA膝关节进行了测试,并在15°至90°的6个不同屈曲角度下加载,载荷逐渐增加。自变量为假体类型(CR 和 PS TKA)、逐渐增加的负荷和膝关节屈曲角 (KFA)。因变量为髌股关节和胫股关节运动学和接触特性:结果显示,在较高的 KFA 下,CR 假体的股骨位置后移明显多于 PS 假体(分别为 36.6 ± 5.2 mm 和 32.5 ± 5.7 mm)。在较高的 KFA 和负荷下,PS 假体的髌股接触力和接触面积明显大于 CR 假体(分别为 102.4 ± 12.5 N 和 88.1 ± 10.9 N)。最后,在 45°、60°、75° 和 90° KFA 屈曲角时,CR 与 PS 种植体的胫股骨接触力明显大于 PS 种植体,在这些屈曲角的所有测试载荷下,CR 和 PS 种植体的平均接触力分别为 246.1 ± 42.1 N 和 192.8 ± 54.8 N:在这项生物力学研究中,CR TKAs 比 PS TKAs 显示出更小的髌骨股骨接触力,但更大的胫骨股骨接触力。在整个关节承受较高载荷和屈曲角度增大的情况下,保留后十字韧带的 CR 设计的股骨后移幅度明显更大,因此髌骨与股骨的接触面积和接触力明显小于 PS 设计。载荷对植入物的不同影响是医生需要考虑的一个重要因素,因为对载荷要求较高的患者应考虑 PS 设计明显大于 CR 设计的髌股接触力和面积。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Load-Dependent Characteristics of Cruciate-Retaining and Posterior-Stabilized Total Knee Arthroplasty: A Biomechanical Study.

Background: Increased load bearing across the patellofemoral and tibiofemoral articulations has been associated with total knee arthroplasty (TKA) complications. Therefore, the purpose of this study was to quantify the biomechanical characteristics of the patellofemoral and tibiofemoral joints and simulate varying weight-bearing demands after posterior cruciate ligament-retaining (CR) and posterior-stabilized (PS) TKAs.

Methods: Eight fresh-frozen cadaveric knees (average age, 68.4 years; range, 40-86 years) were tested using a custom knee system with muscle-loading capabilities. The TKA knees were tested with a CR and then a PS TKA implant and were loaded at 6 different flexion angles from 15° to 90° with progressively increasing loads. The independent variables were the implant types (CR and PS TKA), progressively increased loading, and knee flexion angle (KFA). The dependent variables were the patellofemoral and tibiofemoral kinematics and contact characteristics.

Results: The results showed that at higher KFAs, the position of the femur translated significantly more posterior in CR implants than in PS implants (36.6 ± 5.2 mm and 32.5 ± 5.7 mm, respectively). The patellofemoral contact force and contact area were significantly greater in PS than in CR implants at higher KFAs and loads (102.4 ± 12.5 N and 88.1 ± 10.9 N, respectively). Lastly, the tibiofemoral contact force was significantly greater in the CR than the PS implant at flexion angles of 45°, 60°, 75°, and 90° KFA, the average at these flexion angles for all loads tested being 246.1 ± 42.1 N and 192.8 ± 54.8 N for CR and PS implants, respectively.

Conclusions: In this biomechanical study, CR TKAs showed less patellofemoral contact force, but more tibiofemoral contact force than PS TKAs. For higher loads across the joint and at increased flexion angles, there was significantly more posterior femur translation in the CR design with a preserved posterior cruciate ligament and therefore significantly less patellofemoral contact area and force than in the PS design. The different effects of loading on implants are an important consideration for physicians as patients with higher load demands should consider the significantly greater patellofemoral contact force and area of the PS over the CR design.

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来源期刊
Accounts of Chemical Research
Accounts of Chemical Research 化学-化学综合
CiteScore
31.40
自引率
1.10%
发文量
312
审稿时长
2 months
期刊介绍: Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.
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