卡尔-弗吕格(Carl Flügge),最后的整体卫生学家之一,传染病飞沫传播的发现者。

IF 5.5 3区 医学 Q1 IMMUNOLOGY
Peter R Donald, Stefan H E Kaufmann, Dagmar Schaub, Stephanie Thee, Christoph Lange
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引用次数: 0

摘要

卡尔-弗吕格(Carl Flügge)因推动研究证明咳嗽飞沫传播各种感染,尤其是肺结核而闻名于世。但人们很少意识到,弗吕格在卫生实践的许多其他领域也具有影响力。在弗吕格于 1923 年逝世 100 年后,我们回顾了与弗吕格及其同事和学生的研究相关的文献,并说明他特别重视疾病及其传播可能滋生或预防的环境,包括和研究对任何社区的健康至关重要的各个方面,从实验室的基本微生物学到住房、清洁水供应、营养、卫生、社会经济环境和气候等不同的主题。在他职业生涯的早期,他就提倡母乳喂养,以预防季节性肠胃炎,后来又提倡咳嗽遮蔽,以防止受感染的呼吸道飞沫传播,这不仅涉及肺结核,还涉及其他各种呼吸道感染。弗吕格逝世时,卫生学的现有科学方法已经变得复杂,很难有人像弗吕格那样理解和研究与卫生有关的广泛课题。卡尔-弗吕格是最后一批整体卫生学家之一,也是将环境卫生作为卫生支柱进行研究的鼻祖。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

Carl Flügge, one of the last holistic hygienists and discoverer of droplet transmission of infectious diseases.

Carl Flügge, one of the last holistic hygienists and discoverer of droplet transmission of infectious diseases.

Carl Flügge is best known for the promotion of studies demonstrating the transmission of all manner of infections, but particularly tuberculosis, by coughed droplets. But it is seldom recognised that Flügge was also influential in a number of other fields comprising the practice of hygiene. One-hundred years following his death in 1923, we review literature related to the studies of Flügge and his colleagues and students and illustrate the particular emphasis he laid upon the environment within which disease and its transmission might be fostered or prevented, embracing and studying aspects essential to the health of any community ranging from fundamental microbiology in the laboratory to subjects as disparate as housing, clean water supply, nutrition, sanitation, socio-economic circumstances and climate. Very early in his career he promoted breast feeding for the prevention of seasonal gastro-enteritis and later the sheltering of cough as a means of preventing the transmission of infected respiratory droplets, not only as regards tuberculosis, but also concerning all manner of other respiratory infections. By the time of Flügge's death the complexification of available scientific methodologies comprising hygiene made it difficult for any individual to comprehend and study the wide range of hygiene-related subjects such as Flügge did. Carl Flügge was one of the last holistic hygienists and an originator of the study of environmental health as a pillar of hygiene.

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来源期刊
CiteScore
10.60
自引率
0.00%
发文量
29
审稿时长
1 months
期刊介绍: Medical Microbiology and Immunology (MMIM) publishes key findings on all aspects of the interrelationship between infectious agents and the immune system of their hosts. The journal´s main focus is original research work on intrinsic, innate or adaptive immune responses to viral, bacterial, fungal and parasitic (protozoan and helminthic) infections and on the virulence of the respective infectious pathogens. MMIM covers basic, translational as well as clinical research in infectious diseases and infectious disease immunology. Basic research using cell cultures, organoid, and animal models are welcome, provided that the models have a clinical correlate and address a relevant medical question. The journal also considers manuscripts on the epidemiology of infectious diseases, including the emergence and epidemic spreading of pathogens and the development of resistance to anti-infective therapies, and on novel vaccines and other innovative measurements of prevention. The following categories of manuscripts will not be considered for publication in MMIM: submissions of preliminary work, of merely descriptive data sets without investigation of mechanisms or of limited global interest, manuscripts on existing or novel anti-infective compounds, which focus on pharmaceutical or pharmacological aspects of the drugs, manuscripts on existing or modified vaccines, unless they report on experimental or clinical efficacy studies or provide new immunological information on their mode of action, manuscripts on the diagnostics of infectious diseases, unless they offer a novel concept to solve a pending diagnostic problem, case reports or case series, unless they are embedded in a study that focuses on the anti-infectious immune response and/or on the virulence of a pathogen.
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