Kunyue Li, Chunyun Deng, Daqi Sun, Yuxia Wang, Genxia Li, Lihua Jiang, Tao Wang
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The AUC of the combined indicator (NLR + duration of EA) was higher than that of NLR (AUC = 0.583, 95% confidence interval [CI] 0.53-0.64) and duration of EA (AUC = 0.702, 95% CI 0.66-0.75), reaching 0.715 (95% CI 0.67-0.76; p < 0.001). NLR increased predictive performance for intrapartum fever when added to the duration of EA (net reclassification index 0.076, p = 0.022; integrated discrimination improvement 0.020, p = 0.002).</p><p><strong>Conclusion: </strong>NLR has limited predictive power for intrapartum fever. The combination of NLR and duration of epidural analgesia may be considered a promising predictor for intrapartum maternal fever in parturients undergoing epidural analgesia.</p><p><strong>Synopsis: </strong>The neutrophil-to-lymphocyte ratio is an accessible predictor for the early identification of parturients at risk of intrapartum fever.</p>","PeriodicalId":14164,"journal":{"name":"International Journal of Gynecology & Obstetrics","volume":null,"pages":null},"PeriodicalIF":2.6000,"publicationDate":"2024-08-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Predictive value of neutrophil-to-lymphocyte ratio on admission for intrapartum maternal fever in parturients undergoing epidural analgesia: A retrospective cohort study using propensity score-matched analysis.\",\"authors\":\"Kunyue Li, Chunyun Deng, Daqi Sun, Yuxia Wang, Genxia Li, Lihua Jiang, Tao Wang\",\"doi\":\"10.1002/ijgo.15820\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Objective: </strong>To identify the predictive value of the neutrophil-to-lymphocyte ratio (NLR) on admission for intrapartum maternal fever in parturients undergoing epidural analgesia (EA).</p><p><strong>Methods: </strong>In this retrospective cohort study, propensity score matching (PSM) was applied to address covariates. 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引用次数: 0
摘要
目的确定接受硬膜外镇痛(EA)的产妇入院时中性粒细胞与淋巴细胞比值(NLR)对产褥期发热的预测价值:在这项回顾性队列研究中,采用倾向评分匹配(PSM)来处理协变量。依次进行单变量和多变量回归分析,以找出影响产后发热的因素。结果显示,NLR和EA持续时间是影响产后发热的独立因素:结果:NLR和EA持续时间是产褥热的独立危险因素。综合指标(NLR + EA持续时间)的AUC高于NLR(AUC = 0.583,95%置信区间[CI] 0.53-0.64)和EA持续时间(AUC = 0.702,95% CI 0.66-0.75),达到0.715(95% CI 0.67-0.76;P 结论:NLR和EA持续时间是产后发热的独立危险因素:NLR 对产褥热的预测能力有限。NLR与硬膜外镇痛持续时间的结合可被视为对接受硬膜外镇痛的产妇产期发热的一种有希望的预测指标。
Predictive value of neutrophil-to-lymphocyte ratio on admission for intrapartum maternal fever in parturients undergoing epidural analgesia: A retrospective cohort study using propensity score-matched analysis.
Objective: To identify the predictive value of the neutrophil-to-lymphocyte ratio (NLR) on admission for intrapartum maternal fever in parturients undergoing epidural analgesia (EA).
Methods: In this retrospective cohort study, propensity score matching (PSM) was applied to address covariates. Univariate and multivariate regression analyses were implemented in sequence to find out the factors influencing intrapartum fever. The receiver operating characteristics curve was applied to determine the area under the curve (AUC) of NLR for intrapartum fever.
Results: NLR and duration of EA were independent risk factors for intrapartum fever. The AUC of the combined indicator (NLR + duration of EA) was higher than that of NLR (AUC = 0.583, 95% confidence interval [CI] 0.53-0.64) and duration of EA (AUC = 0.702, 95% CI 0.66-0.75), reaching 0.715 (95% CI 0.67-0.76; p < 0.001). NLR increased predictive performance for intrapartum fever when added to the duration of EA (net reclassification index 0.076, p = 0.022; integrated discrimination improvement 0.020, p = 0.002).
Conclusion: NLR has limited predictive power for intrapartum fever. The combination of NLR and duration of epidural analgesia may be considered a promising predictor for intrapartum maternal fever in parturients undergoing epidural analgesia.
Synopsis: The neutrophil-to-lymphocyte ratio is an accessible predictor for the early identification of parturients at risk of intrapartum fever.
期刊介绍:
The International Journal of Gynecology & Obstetrics publishes articles on all aspects of basic and clinical research in the fields of obstetrics and gynecology and related subjects, with emphasis on matters of worldwide interest.