一名接受177Lu-DOTATATE治疗的神经母细胞瘤患者的123I-MIBG SPECT/CT假阴性和68Ga-DOTATATE PET/CT真阳性。

IF 9.6 3区医学 Q1 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING

Clinical Nuclear Medicine Pub Date : 2025-01-01 Epub Date: 2024-08-02 DOI:10.1097/RLU.0000000000005397

Siqi Li, Yanfeng Xu, Xia Lu, Wei Wang, Jigang Yang

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引用次数: 0

摘要

摘要：一名患有高危神经母细胞瘤的10岁女孩接受了123I-MIBG SPECT/CT和68Ga-DOTATE PET/CT检查，结果均显示有多处骨转移。然而，在接受 177Lu-DOTATATE 治疗后，只有 68Ga-DOTATATE PET/CT 发现了 123I-MIBG SPECT/CT 阴性结果的残余病灶。该病例强调了 68Ga-DOTATATE PET/CT 和 123I-MIBG SPECT/CT 在 177Lu-DOTATATE 治疗后的互补作用。

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A False-Negative 123 I-MIBG SPECT/CT With True-Positive 68 Ga-DOTATATE PET/CT in a Patient With Neuroblastoma Following 177 Lu-DOTATATE Therapy.

Abstract: A 10-year-old girl with high-risk neuroblastoma underwent 123 I-MIBG SPECT/CT and 68 Ga-DOTATE PET/CT, which both showed multiple bone metastases. However, following 177 Lu-DOTATATE therapy, only 68 Ga-DOTATATE PET/CT identified residual lesions with negative 123 I-MIBG SPECT/CT results. The case emphasized the complementary role of 68 Ga-DOTATATE PET/CT and 123 I-MIBG SPECT/CT after 177 Lu-DOTATATE therapy.

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来源期刊

Clinical Nuclear Medicine 医学-核医学

CiteScore

2.90

自引率

31.10%

发文量

1113

审稿时长

2 months

期刊介绍： Clinical Nuclear Medicine is a comprehensive and current resource for professionals in the field of nuclear medicine. It caters to both generalists and specialists, offering valuable insights on how to effectively apply nuclear medicine techniques in various clinical scenarios. With a focus on timely dissemination of information, this journal covers the latest developments that impact all aspects of the specialty. Geared towards practitioners, Clinical Nuclear Medicine is the ultimate practice-oriented publication in the field of nuclear imaging. Its informative articles are complemented by numerous illustrations that demonstrate how physicians can seamlessly integrate the knowledge gained into their everyday practice.