用于激光斑点成像的可调动态组织模型

IF 2.9 2区医学 Q2 BIOCHEMICAL RESEARCH METHODS

Biomedical optics express Pub Date : 2024-06-17 DOI:10.1364/boe.528286

Soumyajit Sarkar, Murali K, Hari M. Varma

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引用次数: 0

摘要

我们介绍了一种新方法，用于设计和实现基于激光斑点的体内血流成像的可调动态组织模型。这种方法依靠随机微分方程（SDE）来控制压电致动器，当激光光源照射时，压电致动器会产生预定义概率密度函数和自相关的斑点。验证实验表明，该模型可产生动态斑点，在相当宽的范围内精确复制表面和深层组织的血流。

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Tunable dynamical tissue phantom for laser speckle imaging

We introduce a novel method to design and implement a tunable dynamical tissue phantom for laser speckle-based in-vivo blood flow imaging. This approach relies on stochastic differential equations (SDE) to control a piezoelectric actuator which, upon illuminated with a laser source, generates speckles of pre-defined probability density function and auto-correlation. The validation experiments show that the phantom can generate dynamic speckles that closely replicate both surfaces as well as deep tissue blood flow for a reasonably wide range and accuracy.

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来源期刊

Biomedical optics express BIOCHEMICAL RESEARCH METHODS-OPTICS

CiteScore

6.80

自引率

11.80%

发文量

633

审稿时长

1 months

期刊介绍： The journal''s scope encompasses fundamental research, technology development, biomedical studies and clinical applications. BOEx focuses on the leading edge topics in the field, including: Tissue optics and spectroscopy Novel microscopies Optical coherence tomography Diffuse and fluorescence tomography Photoacoustic and multimodal imaging Molecular imaging and therapies Nanophotonic biosensing Optical biophysics/photobiology Microfluidic optical devices Vision research.