肠粘液瘤病作为小肠缺血的鉴别诊断。

IF 2.7 4区 医学 Q2 GASTROENTEROLOGY & HEPATOLOGY
Irene López-Rojo, Esther Martin Illana, Laura Castella Bataller, Santiago González-Moreno, Óscar Alonso-Casado, Sara Núñez O'Sullivan, Raquel Oña Navarrete, Gloria Ortega-Pérez
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引用次数: 0

摘要

肠粘孢子菌病是一种罕见的粘孢子菌病,死亡率很高,通常发生在免疫力低下的患者身上,但也有在免疫力正常的人身上发生的病例。发病方式是消化道感染。它通常表现为腹痛、缺血和肠穿孔,通常在手术切除后通过组织病理学确诊。我们介绍了一例 54 岁的女性患者,她患有复发性急性髓性白血病,正在接受多柔比星-阿糖胞苷治疗,并出现发热性中性粒细胞减少症。她的肠道出现了斑点状和进行性缺血,进而演变为肠坏死,经过抗真菌药物治疗和手术治疗后,病情得到控制。手术标本检查发现了无菌的宽菌丝,呈直角分枝,提示为粘孢子菌。这是一种罕见但死亡率极高的病理现象,临床、放射学和手术方面的怀疑对于早期诊断和治疗至关重要,从而改善了患者的预后。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Intestinal mucormycosis as a differential diagnosis of small bowel ischemia.

Intestinal mucormycosis is a rare manifestation of the Mucor fungus, associated with high mortality and typically found in immunocompromised patients, though it has also been described in immunocompetent individuals. The mode of acquisition is digestive. It usually presents as abdominal pain, with ischemia and intestinal perforation, and the diagnosis is often histopathological after surgical resection. We present the case of a 54-year-old female patient with recurrent acute myeloid leukemia undergoing treatment with daunorubicin-cytarabine and experiencing febrile neutropenia. She developed patchy and progressive intestinal ischemia that evolved into intestinal necrosis, which was treated with antifungal medications and surgery. Examination of the surgical specimen revealed aseptate wide hyphae with branching at right angles, suggestive of Mucor fungus. This is a rare but highly mortal pathology in which clinical, radiological, and surgical suspicion is essential for early diagnosis and treatment, thus improving the patient's prognosis.

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来源期刊
CiteScore
2.00
自引率
25.00%
发文量
400
审稿时长
6-12 weeks
期刊介绍: La Revista Española de Enfermedades Digestivas, Órgano Oficial de la Sociedad Española de Patología Digestiva (SEPD), Sociedad Española de Endoscopia Digestiva (SEED) y Asociación Española de Ecografía Digestiva (AEED), publica artículos originales, editoriales, revisiones, casos clínicos, cartas al director, imágenes en patología digestiva, y otros artículos especiales sobre todos los aspectos relativos a las enfermedades digestivas.
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