Lun-Chao Li, Li-Ming Liang, Hong-Ye Ji, Can Zhang, Man Wang, Hong-Sheng Liu
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引用次数: 0
摘要
背景：大便失禁（FI）与 2 型糖尿病（T2D）之间的关系已得到广泛认可，但考虑到人口统计学因素和生活方式变量，目前还缺乏对这种关系的全面了解：方法：采用横断面方法，从 2005-2010 年全国健康与营养调查中确定了 13,510 名 20 岁及以上的成年人。采用多变量逻辑回归模型计算调整后的几率比（ORs），并进一步进行亚组分析和倾向得分分析，以确保结果的稳定性：在 13,510 名成年人中，11.2% 患有 T2D，8.8% 患有 FI。我们发现 T2D 与 FI 之间有很强的关联（OR：1.30；95% CI：1.09-1.54，P 45 是一个关键因素，T2D 与 FI 的关联更强。T2D患者的久坐行为（OR：1.41；95% CI：1.15-1.73）与FI相关：我们的研究强调了美国成年人，尤其是老年 T2D 患者中 T2D 与 FI 之间的重要联系。改变生活方式可降低 FI 风险。关于因果关系和机制还需要更多的研究。
Exploring the association between type 2 diabetes and fecal incontinence in american adults: insights from a large cross-sectional study.
Background: The relationship between fecal incontinence (FI) and type 2 diabetes (T2D) has been well recognized, but a comprehensive understanding of this relationship is lacking, taking into account demographic factors and lifestyle variables.
Methods: Using a cross-sectional approach, 13,510 adults aged 20 years and older were identified from the 2005-2010 National Health and Nutrition Examination Survey. Multivariate logistic regression models were used to calculate the adjusted odds ratios (ORs), and further subgroup analyses and propensity score analysis were performed to ensure stable results.
Results: Among 13,510 adults, 11.2% had T2D, and 8.8% had FI. We found a strong T2D-FI link (OR: 1.30; 95% CI: 1.09-1.54, P < 0.001), even after adjusting for covariates. Age > 45 was a critical factor, with a stronger T2D-FI association. Sedentary behavior (OR: 1.41; 95% CI: 1.15-1.73) in T2D patients were associated with FI.
Conclusions: Our study highlights the significant T2D-FI link in US adults, especially in older T2D patients. Lifestyle changes may reduce FI risk. More research is needed for causality and mechanisms.
期刊介绍：
The International Journal of Colorectal Disease, Clinical and Molecular Gastroenterology and Surgery aims to publish novel and state-of-the-art papers which deal with the physiology and pathophysiology of diseases involving the entire gastrointestinal tract. In addition to original research articles, the following categories will be included: reviews (usually commissioned but may also be submitted), case reports, letters to the editor, and protocols on clinical studies.
The journal offers its readers an interdisciplinary forum for clinical science and molecular research related to gastrointestinal disease.
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