脊柱少见转移灶的立体定向体放射治疗:代表意大利临床肿瘤学和放射治疗协会(AIRO)进行的实践模式调查。

IF 4.2 3区 医学 Q2 ONCOLOGY
Clinical & Experimental Metastasis Pub Date : 2024-10-01 Epub Date: 2024-08-01 DOI:10.1007/s10585-024-10304-3
Francesco Cuccia, Ciro Franzese, Serena Badellino, Paolo Borghetti, Manuela Federico, Giulia Marvaso, Giampaolo Montesi, Antonio Pontoriero, Giuseppe Ferrera, Filippo Alongi, Marta Scorsetti
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引用次数: 0

摘要

背景:寡转移性疾病的生物学和治疗研究小组代表意大利放射治疗和临床肿瘤学协会(AIRO)进行了一项全国性调查,旨在了解当前脊柱寡转移瘤立体定向体放射治疗(SBRT)的实践模式:方法:使用 Surveymonkey 平台发送了一份包含 28 个项目的调查问卷,内容主要涉及与脊柱少见转移瘤 SBRT 相关的人口、临床和技术方面。邀请所有 AIRO 成员填写问卷。然后将数据集中到一个中心进行分析和解读:结果:来自 47 个中心的 53 位放射肿瘤学家完成了问卷调查。大多数人认为最多可同时对3个脊柱少见转移灶进行SBRT治疗(73.5%),而不论脊柱部位(70%)、椎段(85%)和病灶形态特征(71.7%)。在剂量处方方面,3次(58.4%)或5次(34%)的分次疗法是首选方案,在应用大于1毫米的PTV边缘(近90%的参与者)以及理想情况下同时使用MRI和PET成像来改善靶体积和危险器官的划定(67.9%)方面存在很大的一致性:这项意大利全国性调查说明了脊柱少转移灶 SBRT 适应症的实践模式和主要问题。据报道,在SBRT适应症的数字临界值和所涉及的椎体节段方面存在很大的一致性,但在剂量处方和分型方案方面略有差异。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Stereotactic body radiotherapy for spinal oligometastases: a survey on patterns of practice on behalf of the Italian Association of Clinical Oncology and Radiotherapy (AIRO).

Background: The Study Group for the Biology and Treatment of the OligoMetastatic Disease on behalf of the Italian Association of Radiotherapy and Clinical Oncology (AIRO) has conducted a national survey with the aim to depict the current patterns of practice of stereotactic body radiotherapy (SBRT) for spinal oligometastases.

Methods: The Surveymonkey platform was used to send a 28-items questionnaire focused on demographic, clinical and technical aspects related to SBRT for spinal oligometastases. All the AIRO members were invited to fill the questionnaire. Data were then centralized to a single center for analysis and interpretation.

Results: 53 radiation oncologists from 47 centers fulfilled the survey. A complete agreement was observed in proposing SBRT for spinal oligometastases, with the majority considering up to 3 concurrent spine oligometastases feasible for SBRT (73.5%), regardless of spine site (70%), vertebral segment (85%) and morphological features of the lesion (71.7%). Regarding dose prescription, fractionated regimens resulted as the preferred option, either in 3 (58.4%) or five sessions (34%), with a substantial agreement in applying a PTV-margin larger than 1 mm (almost 90% of participants), and ideally using both MRI and PET imaging to improve target volume and organs-at-risk delineation (67.9%).

Conclusions: This national italian survey illustrates the patterns of practice and the main issues for the indication of SBRT for spinal oligometastases. A substantial agreement in the numerical cut-off and vertebral segment involved for SBRT indication was reported, with a slight heterogeneity in terms of dose prescription and fractionation schemes.

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来源期刊
CiteScore
7.80
自引率
5.00%
发文量
55
审稿时长
12 months
期刊介绍: The Journal''s scope encompasses all aspects of metastasis research, whether laboratory-based, experimental or clinical and therapeutic. It covers such areas as molecular biology, pharmacology, tumor biology, and clinical cancer treatment (with all its subdivisions of surgery, chemotherapy and radio-therapy as well as pathology and epidemiology) insofar as these disciplines are concerned with the Journal''s core subject of metastasis formation, prevention and treatment.
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