E Walker, A M Chalke, V L Bland, K E Lind, Z Chen, R M Blew, A O Odegaard, C A Thomson, B Caan, J S Nicholas, C I Valencia, D J Roe, M Allison, P F Schnatz, J Wactawski-Wende, J W Bea
{"title":"用 DXA 导出的腹部游离脂肪量预测绝经后妇女的 MRI 骨骼肌质量。","authors":"E Walker, A M Chalke, V L Bland, K E Lind, Z Chen, R M Blew, A O Odegaard, C A Thomson, B Caan, J S Nicholas, C I Valencia, D J Roe, M Allison, P F Schnatz, J Wactawski-Wende, J W Bea","doi":"10.1139/apnm-2024-0046","DOIUrl":null,"url":null,"abstract":"<p><p>Dual-energy X-ray absorptiometry (DXA) is more available than gold-standard magnetic resonance imaging (MRI), but DXA ability to estimate abdominal skeletal muscle mass (SMM) is unknown. DXA-derived abdominal fat-free mass (FFM; Hologic QDR2000 or QDR4500w) was correlated with single-slice MRI SMM at L4 (<i>N</i> = 69; r QDR2000 = 0.71, QDR4500w = 0.69; <i>p</i> < 0.0001). Linear regression to predict SMM, including DXA FFM, BMI, and age, resulted in an R-squared of 0.72 and 0.65 for QDR2000 and QDR4500. Bland-Altman limits of agreement were ±21 and ±31 g for 2-3 standard deviations from the mean difference. DXA predicted abdominal SSM is a moderate proxy for MRI abdominal SMM.</p>","PeriodicalId":93878,"journal":{"name":"Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2024-07-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"DXA-derived abdominal fat-free mass to predict MRI skeletal muscle mass in postmenopausal women.\",\"authors\":\"E Walker, A M Chalke, V L Bland, K E Lind, Z Chen, R M Blew, A O Odegaard, C A Thomson, B Caan, J S Nicholas, C I Valencia, D J Roe, M Allison, P F Schnatz, J Wactawski-Wende, J W Bea\",\"doi\":\"10.1139/apnm-2024-0046\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>Dual-energy X-ray absorptiometry (DXA) is more available than gold-standard magnetic resonance imaging (MRI), but DXA ability to estimate abdominal skeletal muscle mass (SMM) is unknown. DXA-derived abdominal fat-free mass (FFM; Hologic QDR2000 or QDR4500w) was correlated with single-slice MRI SMM at L4 (<i>N</i> = 69; r QDR2000 = 0.71, QDR4500w = 0.69; <i>p</i> < 0.0001). Linear regression to predict SMM, including DXA FFM, BMI, and age, resulted in an R-squared of 0.72 and 0.65 for QDR2000 and QDR4500. Bland-Altman limits of agreement were ±21 and ±31 g for 2-3 standard deviations from the mean difference. DXA predicted abdominal SSM is a moderate proxy for MRI abdominal SMM.</p>\",\"PeriodicalId\":93878,\"journal\":{\"name\":\"Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2024-07-30\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1139/apnm-2024-0046\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1139/apnm-2024-0046","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
摘要
双能 X 射线吸收测定法（DXA）比黄金标准的磁共振成像（MRI）更方便使用，但 DXA 估算腹部骨骼肌质量（SMM）的能力尚不清楚。DXA 导出的腹部无脂肪质量（FFM；Hologic QDR2000 或 QDR4500w）与 L4 处单片 MRI SMM 存在相关性（N = 69；r QDR2000=0.71, QDR4500w=0.69; p
DXA-derived abdominal fat-free mass to predict MRI skeletal muscle mass in postmenopausal women.
Dual-energy X-ray absorptiometry (DXA) is more available than gold-standard magnetic resonance imaging (MRI), but DXA ability to estimate abdominal skeletal muscle mass (SMM) is unknown. DXA-derived abdominal fat-free mass (FFM; Hologic QDR2000 or QDR4500w) was correlated with single-slice MRI SMM at L4 (N = 69; r QDR2000 = 0.71, QDR4500w = 0.69; p < 0.0001). Linear regression to predict SMM, including DXA FFM, BMI, and age, resulted in an R-squared of 0.72 and 0.65 for QDR2000 and QDR4500. Bland-Altman limits of agreement were ±21 and ±31 g for 2-3 standard deviations from the mean difference. DXA predicted abdominal SSM is a moderate proxy for MRI abdominal SMM.
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