头颈部重建中深动脉穿孔器皮瓣的手术效果:系统回顾和荟萃分析。

IF 4.6 Q2 MATERIALS SCIENCE, BIOMATERIALS
Filippo Marchi, Andrea Iandelli, Gian Marco Pace, Elisa Bellini, Alessandro Tirrito, Andrea Costantino, Luca Cerri, Antonio Greco, Antonella Polimeni, Giampiero Parrinello, Giorgio Peretti, Armando De Virgilio
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引用次数: 0

摘要

研究目的本研究旨在评估深动脉穿孔器(PAP)皮瓣在头颈部重建中的疗效:方法:对皮瓣存活率(主要结果)、主要并发症再手术率和总体并发症发生率(次要结果)进行单臂荟萃分析:搜索策略共搜索到 295 篇潜在相关文献,其中 13 篇被纳入。共纳入 305 名患者(男性:80.8%,n = 232/281),中位年龄为 56.1 岁(n = 305/305;95% CI 53.9-63),他们因头颈部缺损接受了 307 例 PAP 皮瓣重建术。皮瓣存活率为 100%(n = 306/307;95% CI 99.6%-100%),主要并发症的再手术率为 3.7%(n = 15/307;95% CI 1.85%-6.1%),总并发症率为 26.5%(n = 92/307;95% CI 15.7%-38.9%)。显著的术后并发症包括伤口开裂(n = 15/307,4.9%)、延迟愈合(n = 14/307,4.6%)和伤口感染(n = 12/307,3.9%)。部分皮瓣坏死和血肿发生率为 2.6%(8/307),动脉和静脉血栓形成率分别为 0.7%(2/307)和 1.3%(4/307):结论:PAP皮瓣在头颈部重建中的应用显示出多个有利方面,如皮瓣失败率极低、可实现不同尺寸的多功能性以及并发症发生率相对较低。在头颈部重建中,PAP皮瓣可被视为传统软组织游离皮瓣的替代品。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Surgical outcomes of profunda artery perforator flap in head and neck reconstruction: A systematic review and meta-analysis.

Objective: This study aims to evaluate the efficacy of the profunda artery perforator (PAP) flap in head and neck reconstruction.

Methods: A single arm meta-analysis was performed for flap survival rate (primary outcome), reoperation for major complication, and overall complication rates (secondary outcomes).

Results: The search strategy yielded a total of 295 potentially relevant publications, of which 13 were included. A total of 305 patients (males: 80.8%, n = 232/281), with a median age of 56.1 years (n = 305/305; 95% CI 53.9-63), who underwent a total of 307 PAP flap reconstructions for head and neck defects were included. Flap survival rate was 100% (n = 306/307; 95% CI 99.6%-100%), with a reoperation rate for major complications of 3.7% (n = 15/307; 95% CI 1.85%-6.1%) and an overall complication rate of 26.5% (n = 92/307; 95% CI 15.7%-38.9%). Notable postoperative complications included wound dehiscence (n = 15/307, 4.9%), delayed healing (n = 14/307, 4.6%), and wound infection (n = 12/307, 3.9%). Partial flap necrosis and hematoma occurred in 2.6% of cases (n = 8/307), while arterial and venous thrombosis were documented in 0.7% (n = 2/307) and 1.3%, respectively (n = 4/307).

Conclusion: The application of the PAP flap in head and neck reconstructions showed several favorable aspects, such as an exceptionally low flap failure rate, versatility in achieving variable dimensions, and a relatively low incidence of complications. PAP flap might be considered as a compelling alternative to the traditionally employed soft tissue free flaps in head and neck reconstruction.

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来源期刊
ACS Applied Bio Materials
ACS Applied Bio Materials Chemistry-Chemistry (all)
CiteScore
9.40
自引率
2.10%
发文量
464
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