三向细胞器连接控制着 PI(4)P 代谢和线粒体分裂。

IF 7.4 1区生物学 Q1 CELL BIOLOGY

Journal of Cell Biology Pub Date : 2024-09-02 Epub Date: 2024-07-31 DOI:10.1083/jcb.202407125

York Posor, Volker Haucke

引用次数: 0

摘要

膜接触点（MCS）有助于细胞器之间的交流。Casler 等人（https://doi.org/10.1083/jcb.202308144）的研究表明，线粒体、内质网（ER）和质膜（PM）之间的三方 MCS 调节着线粒体的分裂和 4-磷酸肌醇磷脂 [PI(4)P] 在质膜上的分布。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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A three-way organelle junction controls PI(4)P metabolism and mitochondrial division.

Membrane contact sites (MCS) facilitate communication between organelles. Casler et al. (https://doi.org/10.1083/jcb.202308144) show that tripartite MCS between mitochondria, the endoplasmic reticulum (ER), and the plasma membrane (PM) regulate mitochondrial division and the distribution of phosphatidylinositol 4-phosphate [PI(4)P] on the PM.

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来源期刊

Journal of Cell Biology 生物-细胞生物学

CiteScore

12.60

自引率

2.60%

发文量

213

审稿时长

1 months

期刊介绍： The Journal of Cell Biology (JCB) is a comprehensive journal dedicated to publishing original discoveries across all realms of cell biology. We invite papers presenting novel cellular or molecular advancements in various domains of basic cell biology, along with applied cell biology research in diverse systems such as immunology, neurobiology, metabolism, virology, developmental biology, and plant biology. We enthusiastically welcome submissions showcasing significant findings of interest to cell biologists, irrespective of the experimental approach.