{"title":"结晶:以虚拟模式部署的研究级实验为基础,解决化学工程课堂中的晶体成核问题","authors":"Mayank Vashishtha , Shubhangi Kakkar , Mahmoud Ranjbar, K. Vasanth Kumar","doi":"10.1016/j.ece.2024.07.001","DOIUrl":null,"url":null,"abstract":"<div><p>Crystallization via nucleation can isolate active pharmaceutical ingredients from their crudes. While chemical engineering textbooks provide theoretical knowledge on crystallization and nucleation theories, they often fall short in providing provide practical insights on the nucleation mechanism. To bridge this gap, we introduced a virtual experiment on nucleation in second-year chemical engineering classrooms. The main goal is to educate students on crystallization procedures in research and process industries, teaching them how to analyse and manage collected data while integrating theoretical knowledge. This includes conveying the kind of information that can be obtained from a crystallisation process and instructing students on how to analyse and manage the data collected in the light of the theories learned. We devised an original chemical engineering problem on nucleation, derived directly from the raw data collected in the classroom from virtual experiments. This method differs from the conventional approach of solving standard textbook problems. The textbook problems, regrettably often lack crucial information on how nucleation rate or surface free energy are directly obtained from raw data. By the conclusion of the virtual experiment, students have acquired a comprehensive understanding encompassing both practical and theoretical aspects of crystallization, with a particular focus on nucleation. The methodologies elucidated in this study can be applied across a spectrum of chemical engineering modules, including process engineering, unit operations in chemical engineering, mass transfer, and can even be integrated into specialized courses dedicated to crystallization.</p></div>","PeriodicalId":48509,"journal":{"name":"Education for Chemical Engineers","volume":"49 ","pages":"Pages 12-25"},"PeriodicalIF":3.5000,"publicationDate":"2024-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1749772824000186/pdfft?md5=7403bb398d99b50de759d31b1ec85016&pid=1-s2.0-S1749772824000186-main.pdf","citationCount":"0","resultStr":"{\"title\":\"Crystallisation: Solving crystal nucleation problem in the chemical engineering classroom based on the research grade experiments deployed in virtual mode\",\"authors\":\"Mayank Vashishtha , Shubhangi Kakkar , Mahmoud Ranjbar, K. Vasanth Kumar\",\"doi\":\"10.1016/j.ece.2024.07.001\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><p>Crystallization via nucleation can isolate active pharmaceutical ingredients from their crudes. While chemical engineering textbooks provide theoretical knowledge on crystallization and nucleation theories, they often fall short in providing provide practical insights on the nucleation mechanism. To bridge this gap, we introduced a virtual experiment on nucleation in second-year chemical engineering classrooms. The main goal is to educate students on crystallization procedures in research and process industries, teaching them how to analyse and manage collected data while integrating theoretical knowledge. This includes conveying the kind of information that can be obtained from a crystallisation process and instructing students on how to analyse and manage the data collected in the light of the theories learned. We devised an original chemical engineering problem on nucleation, derived directly from the raw data collected in the classroom from virtual experiments. This method differs from the conventional approach of solving standard textbook problems. The textbook problems, regrettably often lack crucial information on how nucleation rate or surface free energy are directly obtained from raw data. By the conclusion of the virtual experiment, students have acquired a comprehensive understanding encompassing both practical and theoretical aspects of crystallization, with a particular focus on nucleation. The methodologies elucidated in this study can be applied across a spectrum of chemical engineering modules, including process engineering, unit operations in chemical engineering, mass transfer, and can even be integrated into specialized courses dedicated to crystallization.</p></div>\",\"PeriodicalId\":48509,\"journal\":{\"name\":\"Education for Chemical Engineers\",\"volume\":\"49 \",\"pages\":\"Pages 12-25\"},\"PeriodicalIF\":3.5000,\"publicationDate\":\"2024-07-25\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.sciencedirect.com/science/article/pii/S1749772824000186/pdfft?md5=7403bb398d99b50de759d31b1ec85016&pid=1-s2.0-S1749772824000186-main.pdf\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Education for Chemical Engineers\",\"FirstCategoryId\":\"95\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S1749772824000186\",\"RegionNum\":2,\"RegionCategory\":\"教育学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"EDUCATION, SCIENTIFIC DISCIPLINES\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Education for Chemical Engineers","FirstCategoryId":"95","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S1749772824000186","RegionNum":2,"RegionCategory":"教育学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"EDUCATION, SCIENTIFIC DISCIPLINES","Score":null,"Total":0}
Crystallisation: Solving crystal nucleation problem in the chemical engineering classroom based on the research grade experiments deployed in virtual mode
Crystallization via nucleation can isolate active pharmaceutical ingredients from their crudes. While chemical engineering textbooks provide theoretical knowledge on crystallization and nucleation theories, they often fall short in providing provide practical insights on the nucleation mechanism. To bridge this gap, we introduced a virtual experiment on nucleation in second-year chemical engineering classrooms. The main goal is to educate students on crystallization procedures in research and process industries, teaching them how to analyse and manage collected data while integrating theoretical knowledge. This includes conveying the kind of information that can be obtained from a crystallisation process and instructing students on how to analyse and manage the data collected in the light of the theories learned. We devised an original chemical engineering problem on nucleation, derived directly from the raw data collected in the classroom from virtual experiments. This method differs from the conventional approach of solving standard textbook problems. The textbook problems, regrettably often lack crucial information on how nucleation rate or surface free energy are directly obtained from raw data. By the conclusion of the virtual experiment, students have acquired a comprehensive understanding encompassing both practical and theoretical aspects of crystallization, with a particular focus on nucleation. The methodologies elucidated in this study can be applied across a spectrum of chemical engineering modules, including process engineering, unit operations in chemical engineering, mass transfer, and can even be integrated into specialized courses dedicated to crystallization.
期刊介绍:
Education for Chemical Engineers was launched in 2006 with a remit to publisheducation research papers, resource reviews and teaching and learning notes. ECE is targeted at chemical engineering academics and educators, discussing the ongoingchanges and development in chemical engineering education. This international title publishes papers from around the world, creating a global network of chemical engineering academics. Papers demonstrating how educational research results can be applied to chemical engineering education are particularly welcome, as are the accounts of research work that brings new perspectives to established principles, highlighting unsolved problems or indicating direction for future research relevant to chemical engineering education. Core topic areas: -Assessment- Accreditation- Curriculum development and transformation- Design- Diversity- Distance education-- E-learning Entrepreneurship programs- Industry-academic linkages- Benchmarking- Lifelong learning- Multidisciplinary programs- Outreach from kindergarten to high school programs- Student recruitment and retention and transition programs- New technology- Problem-based learning- Social responsibility and professionalism- Teamwork- Web-based learning