{"title":"嗜睡症伴惊厥患者治疗诱发的躁狂症病例报告","authors":"Roberto Galea, Elsa Cassar, Anthony Zahra","doi":"10.1016/j.hmedic.2024.100101","DOIUrl":null,"url":null,"abstract":"<div><p>Modafinil is a psychostimulant primarily used to manage sleep disorders, multiple sclerosis, and both unipolar and bipolar depression. Despite the risk of precipitating mania and psychosis, it is also employed as a non-antipsychotic augmentation therapy in schizophrenia. Only two case reports documented managing mania and narcolepsy with co-prescribed lithium carbonate. Below we discuss a case of treatment-induced mania in a gentleman diagnosed with Bipolar Affective Disorder (BPAD) comorbid with type I narcolepsy who was prescribed modafinil, venlafaxine and fluoxetine. The successful mood stabilisation with lithium carbonate suggests a potential role for mood stabilisers in such cases. This case report underscores the complexity of treating narcolepsy with comorbid psychiatric conditions and the importance of comprehensive evaluation and tailored management.</p></div>","PeriodicalId":100908,"journal":{"name":"Medical Reports","volume":"6 ","pages":"Article 100101"},"PeriodicalIF":0.0000,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2949918624000664/pdfft?md5=f676c87fd4921f70fe9b2b5d23096e67&pid=1-s2.0-S2949918624000664-main.pdf","citationCount":"0","resultStr":"{\"title\":\"Treatment-induced mania in a patient with narcolepsy with cataplexy case report\",\"authors\":\"Roberto Galea, Elsa Cassar, Anthony Zahra\",\"doi\":\"10.1016/j.hmedic.2024.100101\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><p>Modafinil is a psychostimulant primarily used to manage sleep disorders, multiple sclerosis, and both unipolar and bipolar depression. Despite the risk of precipitating mania and psychosis, it is also employed as a non-antipsychotic augmentation therapy in schizophrenia. Only two case reports documented managing mania and narcolepsy with co-prescribed lithium carbonate. Below we discuss a case of treatment-induced mania in a gentleman diagnosed with Bipolar Affective Disorder (BPAD) comorbid with type I narcolepsy who was prescribed modafinil, venlafaxine and fluoxetine. The successful mood stabilisation with lithium carbonate suggests a potential role for mood stabilisers in such cases. This case report underscores the complexity of treating narcolepsy with comorbid psychiatric conditions and the importance of comprehensive evaluation and tailored management.</p></div>\",\"PeriodicalId\":100908,\"journal\":{\"name\":\"Medical Reports\",\"volume\":\"6 \",\"pages\":\"Article 100101\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2024-08-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.sciencedirect.com/science/article/pii/S2949918624000664/pdfft?md5=f676c87fd4921f70fe9b2b5d23096e67&pid=1-s2.0-S2949918624000664-main.pdf\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Medical Reports\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S2949918624000664\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Medical Reports","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2949918624000664","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Treatment-induced mania in a patient with narcolepsy with cataplexy case report
Modafinil is a psychostimulant primarily used to manage sleep disorders, multiple sclerosis, and both unipolar and bipolar depression. Despite the risk of precipitating mania and psychosis, it is also employed as a non-antipsychotic augmentation therapy in schizophrenia. Only two case reports documented managing mania and narcolepsy with co-prescribed lithium carbonate. Below we discuss a case of treatment-induced mania in a gentleman diagnosed with Bipolar Affective Disorder (BPAD) comorbid with type I narcolepsy who was prescribed modafinil, venlafaxine and fluoxetine. The successful mood stabilisation with lithium carbonate suggests a potential role for mood stabilisers in such cases. This case report underscores the complexity of treating narcolepsy with comorbid psychiatric conditions and the importance of comprehensive evaluation and tailored management.
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