{"title":"埃塞俄比亚圣彼得结核病专科医院接受高效抗逆转录病毒治疗的艾滋病患者中的结核病合并感染及相关因素:一项为期五年的回顾性研究","authors":"Dereje Getaw, F. Tigu","doi":"10.4314/ahs.v24i2.7","DOIUrl":null,"url":null,"abstract":"Background: TB and HIV are the two widely distributed and successful microbial diseases which impose public health problems globally. \nObjectives: The study aimed to determine the prevalence and associated factors of TB among people living with HIV (PLHIV). \nMethods: A retrospective study was conducted among PLHIV at Saint Peter’s TB Specialized Hospital (SPTSH). Study participants were selected by random sampling technique. Logistic regression analyses were employed to determine the associations between dependent and independent variables. P ≤ 0.05 was taken as statistically significant. \nResults: The prevalence of TB among PLHIV in the entire study population was 24.6%. The proportion of pulmonary TB (PTB), disseminated TB (DTB) and extra pulmonary TB (EPTB), were 49 (57.6%), 9 (10.6%) and 27 (31.8%), respectively. Logistic regression analysis showed that PLHIV who are non-adhered to ART (AOR = 51.6, 95% CI 24.18 - 387), HAART duration of > 35 months (AOR = 0.39, 95% CI 0.198 - 2.10) and WHO clinical stage IV (AOR = 40.14, 95% CI15.14 -106.44), were significantly associated with TB/HIV co-infection. \nConclusions: TB co-infection is the major public health issue of PLHIV. Special emphasis is required to reduce the incidence of TB/HIV associated morbidity and mortality among PLHIV. \nKeywords: Adherence; ETB; prevalence; TB/HIV co-infection.","PeriodicalId":94295,"journal":{"name":"African health sciences","volume":"72 s320","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2024-07-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"TB co-infection and associated factors among HIV patients attending highly active antiretroviral therapy in Saint Peter’s TB Specialized Hospital, Ethiopia: a five years retrospective study\",\"authors\":\"Dereje Getaw, F. Tigu\",\"doi\":\"10.4314/ahs.v24i2.7\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Background: TB and HIV are the two widely distributed and successful microbial diseases which impose public health problems globally. \\nObjectives: The study aimed to determine the prevalence and associated factors of TB among people living with HIV (PLHIV). \\nMethods: A retrospective study was conducted among PLHIV at Saint Peter’s TB Specialized Hospital (SPTSH). Study participants were selected by random sampling technique. Logistic regression analyses were employed to determine the associations between dependent and independent variables. P ≤ 0.05 was taken as statistically significant. \\nResults: The prevalence of TB among PLHIV in the entire study population was 24.6%. The proportion of pulmonary TB (PTB), disseminated TB (DTB) and extra pulmonary TB (EPTB), were 49 (57.6%), 9 (10.6%) and 27 (31.8%), respectively. Logistic regression analysis showed that PLHIV who are non-adhered to ART (AOR = 51.6, 95% CI 24.18 - 387), HAART duration of > 35 months (AOR = 0.39, 95% CI 0.198 - 2.10) and WHO clinical stage IV (AOR = 40.14, 95% CI15.14 -106.44), were significantly associated with TB/HIV co-infection. \\nConclusions: TB co-infection is the major public health issue of PLHIV. Special emphasis is required to reduce the incidence of TB/HIV associated morbidity and mortality among PLHIV. \\nKeywords: Adherence; ETB; prevalence; TB/HIV co-infection.\",\"PeriodicalId\":94295,\"journal\":{\"name\":\"African health sciences\",\"volume\":\"72 s320\",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2024-07-11\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"African health sciences\",\"FirstCategoryId\":\"0\",\"ListUrlMain\":\"https://doi.org/10.4314/ahs.v24i2.7\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"African health sciences","FirstCategoryId":"0","ListUrlMain":"https://doi.org/10.4314/ahs.v24i2.7","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
摘要
背景:肺结核和艾滋病毒是两种分布广泛且成功治愈的微生物疾病,给全球带来了公共卫生问题。研究目的本研究旨在确定肺结核在艾滋病病毒感染者(PLHIV)中的发病率和相关因素。研究方法在圣彼得结核病专科医院(SPTSH)对艾滋病毒感染者进行了一项回顾性研究。研究对象通过随机抽样技术选出。采用逻辑回归分析确定因变量和自变量之间的关联。P≤0.05为具有统计学意义。结果在整个研究人群中,PLHIV 的结核病患病率为 24.6%。肺结核(PTB)、播散性肺结核(DTB)和肺外结核(EPTB)的比例分别为 49(57.6%)、9(10.6%)和 27(31.8%)。逻辑回归分析表明,未坚持抗逆转录病毒疗法的 PLHIV(AOR = 51.6,95% CI 24.18 - 387)、HAART 持续时间大于 35 个月(AOR = 0.39,95% CI 0.198 - 2.10)和 WHO 临床分期 IV(AOR = 40.14,95% CI 15.14 -106.44)与结核病/艾滋病毒合并感染显著相关。结论结核病合并感染是 PLHIV 的主要公共卫生问题。需要特别重视降低 PLHIV 中与 TB/HIV 相关的发病率和死亡率。关键词依从性;ETB;流行率;结核病/艾滋病毒合并感染。
TB co-infection and associated factors among HIV patients attending highly active antiretroviral therapy in Saint Peter’s TB Specialized Hospital, Ethiopia: a five years retrospective study
Background: TB and HIV are the two widely distributed and successful microbial diseases which impose public health problems globally.
Objectives: The study aimed to determine the prevalence and associated factors of TB among people living with HIV (PLHIV).
Methods: A retrospective study was conducted among PLHIV at Saint Peter’s TB Specialized Hospital (SPTSH). Study participants were selected by random sampling technique. Logistic regression analyses were employed to determine the associations between dependent and independent variables. P ≤ 0.05 was taken as statistically significant.
Results: The prevalence of TB among PLHIV in the entire study population was 24.6%. The proportion of pulmonary TB (PTB), disseminated TB (DTB) and extra pulmonary TB (EPTB), were 49 (57.6%), 9 (10.6%) and 27 (31.8%), respectively. Logistic regression analysis showed that PLHIV who are non-adhered to ART (AOR = 51.6, 95% CI 24.18 - 387), HAART duration of > 35 months (AOR = 0.39, 95% CI 0.198 - 2.10) and WHO clinical stage IV (AOR = 40.14, 95% CI15.14 -106.44), were significantly associated with TB/HIV co-infection.
Conclusions: TB co-infection is the major public health issue of PLHIV. Special emphasis is required to reduce the incidence of TB/HIV associated morbidity and mortality among PLHIV.
Keywords: Adherence; ETB; prevalence; TB/HIV co-infection.