根据近邻匹配分析技术估算乌干达五岁以下儿童患疟疾的风险

African health sciences Pub Date : 2024-07-11 DOI:10.4314/ahs.v24i2.20

Charles Natuhamya

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引用次数: 0

摘要

导言：尽管为减少疟疾做出了努力，但疟疾仍然是全球的负担，尤其是五岁以下儿童。最推荐的病媒控制方法是使用驱虫蚊帐（ITN）或长效驱虫蚊帐（LLIN）以及室内滞留喷洒（IRS）。然而，这些创新方法对五岁以下儿童疟疾风险的影响可能并不相同。因此，本研究旨在利用近邻匹配分析法评估：驱虫蚊帐/长效驱虫蚊帐对疟疾风险的影响、室内滞留喷洒对疟疾风险的影响以及驱虫蚊帐/长效驱虫蚊帐对室内滞留喷洒的影响。方法：使用近邻匹配分析法对治疗单位和对照单位进行匹配，方法是以每个治疗单位为对象，搜索对照单位的近邻，不进行替换。结果结果显示，驱虫蚊帐/长效驱虫蚊帐和 IRS 对疟疾风险的影响分别为[ATET=-0.05; 95% CI= -0.07 -0.02]和[ATET=-0.12; 95% CI= -0.15 -0.09]。研究还发现，驱虫蚊帐/长效驱虫蚊帐对 IRS 有明显的积极影响 [ATET=0.03; 95% CI= 0.01 - 0.05]。结论实施有效使用 ITN/LLIN 和 IRS 的政策和计划可以减轻乌干达五岁以下儿童的疟疾负担。关键词室内滞留喷洒；驱虫蚊帐；长效驱虫蚊帐；疟疾；近邻匹配；治疗效果；乌干达。

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Estimating the under-five malaria risk in Uganda based on the nearest neighbour matched analysis technique

Introduction: Malaria still remains a global burden especially in the under-five despite efforts made towards reducing it. The most recommended vector control methods are; use of insecticide treated nets (ITNs) or long lasting insecticide nets (LLINs) and use of indoor residual spraying (IRS). However, these innovations may not have the same effect on malaria risk in the under-five. This study therefore aimed at assessing; the effect of ITNs/LLINs on malaria risk, the effect of IRS on malaria risk, and the effect of ITNs/LLINs on IRS, using nearest neighbours matched analysis. Methods: Nearest neighbour matched analysis was used to match the treated and control units by taking each treated unit and searching for the control unit with the nearest neighbours without replacement. Results: The results revealed a significant and negative effect of ITNs/LLINs and IRS on malaria risk [ATET=-0.05; 95% CI= -0.07 – -0.02] and [ATET=-0.12; 95% CI= -0.15 – -0.09] respectively. It also found a significant and positive effect of ITNs/LLINs on IRS [ATET=0.03; 95% CI= 0.01 – 0.05]. Conclusions: The implementation of policies and programs towards effective use of ITN/LLIN and IRS can reduce the burden of under-five malaria in Uganda. Keywords: Indoor residual spraying; insecticide treated nets; long lasting insecticide nets; Malaria; nearest neighbour matching; treatment effects; Uganda.

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African health sciences

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