新型布洛芬-5-氨基水杨酸配体衍生的三苯基锡（IV）复合物的抗氧化特性：合成与表征

IF 1.3 4区化学 Q3 CHEMISTRY, MULTIDISCIPLINARY

Bulletin of the Chemical Society of Ethiopia Pub Date : 2024-07-12 DOI:10.4314/bcse.v38i5.11

Mohanned Ali Abed-AL Zahra, Angham G. Hadi

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引用次数: 0

摘要

本研究通过布洛芬和 5-氨基水杨酸（IAS）的缩合反应制备了新的配体，并利用制备的配体制备了三种三硼锡(IV)盐的配合物，从而得到了相应的配合物。配体（IAS）和配合物通过红外光谱、（锡、质子和碳）磁共振（1H、13C、119Sn NMR）、元素分析等多种技术进行了表征。此外，还研究了复合物的抗氧化活性。它是通过两种方法产生的：DPPH 和 CUPRAC。由于络合物中锡元素的存在，所产生的络合物比配体具有更高的抑制率。络合物 1（三苯基锡-IAS）的抗氧化活性也高于其他化合物。关键词：配体，抗氧化活性，三有机锡（IV），DPPH 法，CUPRAC 法 Bull.Chem.Soc.2024, 38(5), 1329-1336. DOI: https://dx.doi.org/10.4314/bcse.v38i5.11

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Antioxidant properties of triphenyltin(IV) complexes derived from a novel ibuprofen-5-aminosalicylic acid ligand: synthesis and characterization

In this study, new ligand was prepared by condensation reaction between Ibuprofen and 5-amino salicylic acid (IAS), this prepared ligand was used to prepare three complexes of triorgnotin(IV) salts to obtain the corresponding complexes. The ligand (IAS) and complexes were characterized by several techniques such as infrared spectroscopy, (tin, proton and carbon) magnetic resonance (1H, 13C, 119Sn NMR), elemental analyses. The antioxidant activity of the complexes was also studied. It was produced by two methods: DPPH and CUPRAC. The resulting complexes gave a higher rate of inhibition than the ligand due to the presence of the tin element in the complexes. Complex 1 (tri phenyltin-IAS) also shown greater antioxidant activity than the other compounds. KEY WORDS: Ligand, Antioxidant activity, Triorganotin(IV), DPPH method, CUPRAC method Bull. Chem. Soc. Ethiop. 2024, 38(5), 1329-1336. DOI: https://dx.doi.org/10.4314/bcse.v38i5.11

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来源期刊

Bulletin of the Chemical Society of Ethiopia 化学-化学综合

CiteScore

2.20

自引率

8.30%

发文量

113

审稿时长

6-12 weeks

期刊介绍： The Bulletin of the Chemical Society of Ethiopia (BCSE) is a triannual publication of the Chemical Society of Ethiopia. The BCSE is an open access and peer reviewed journal. The BCSE invites contributions in any field of basic and applied chemistry.