Susan Banda, I. Kohler, Hans-Peter Kohler, S. C. Chichlowska
{"title":"马拉维农村地区 45 岁及以上高血压成人的健康相关生活质量及其预测因素:一项基于人口的研究","authors":"Susan Banda, I. Kohler, Hans-Peter Kohler, S. C. Chichlowska","doi":"10.4314/mmj.v36i2.6","DOIUrl":null,"url":null,"abstract":"Background Hypertension is associated with impaired Health-Related Quality of Life (HRQOL), but its assessment is rarely done in the management of hypertension in Malawi. This study aimed to evaluate the HRQOL of hypertensive adults compared to normotensive individuals and suggest possible predictors of HRQOL in hypertensive adults in rural Malawi. MethodsThis was a cross-sectional study utilizing data from the 2017 Mature Adults Cohort of the Malawi Longitudinal Study for Families and Health (MLSFH-MAC). The study included 1489 adults aged 45 and above from Rumphi, Mchinji, and Balaka districts. HRQOL was measured using the Short Form 12-item (SF-12) questionnaire. Univariable logistic regression, followed by multivariable logistic regression, was used to identify independent predictors of HRQOL in hypertensive adults. A p-value of <0.05 was considered statistically significant. ResultsThe prevalence of hypertension was 44.1%. Hypertensive participants had significantly lower physical and mental HRQOL than their normotensive counterparts (p<0.05). Multiple regression analysis showed that female sex, age, presence of comorbidities, and use of antihypertensive medications were significant predictors of poor physical HRQOL. Being female was a significant predictor of poor mental HRQOL (all p-values <0.05).ConclusionIn rural Malawi, hypertensive adults presented with lower physical and mental HRQOL. Interventions aimed at improving HRQOL should focus on hypertensive adults who are female, older, on antihypertensive medications, and with comorbidities.","PeriodicalId":1,"journal":{"name":"Accounts of Chemical Research","volume":" 4","pages":""},"PeriodicalIF":16.4000,"publicationDate":"2024-07-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Health-related quality of life and its predictors among hypertensive adults 45 years and older in rural Malawi: a population-based study\",\"authors\":\"Susan Banda, I. Kohler, Hans-Peter Kohler, S. C. Chichlowska\",\"doi\":\"10.4314/mmj.v36i2.6\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Background Hypertension is associated with impaired Health-Related Quality of Life (HRQOL), but its assessment is rarely done in the management of hypertension in Malawi. This study aimed to evaluate the HRQOL of hypertensive adults compared to normotensive individuals and suggest possible predictors of HRQOL in hypertensive adults in rural Malawi. MethodsThis was a cross-sectional study utilizing data from the 2017 Mature Adults Cohort of the Malawi Longitudinal Study for Families and Health (MLSFH-MAC). The study included 1489 adults aged 45 and above from Rumphi, Mchinji, and Balaka districts. HRQOL was measured using the Short Form 12-item (SF-12) questionnaire. Univariable logistic regression, followed by multivariable logistic regression, was used to identify independent predictors of HRQOL in hypertensive adults. A p-value of <0.05 was considered statistically significant. ResultsThe prevalence of hypertension was 44.1%. Hypertensive participants had significantly lower physical and mental HRQOL than their normotensive counterparts (p<0.05). Multiple regression analysis showed that female sex, age, presence of comorbidities, and use of antihypertensive medications were significant predictors of poor physical HRQOL. Being female was a significant predictor of poor mental HRQOL (all p-values <0.05).ConclusionIn rural Malawi, hypertensive adults presented with lower physical and mental HRQOL. Interventions aimed at improving HRQOL should focus on hypertensive adults who are female, older, on antihypertensive medications, and with comorbidities.\",\"PeriodicalId\":1,\"journal\":{\"name\":\"Accounts of Chemical Research\",\"volume\":\" 4\",\"pages\":\"\"},\"PeriodicalIF\":16.4000,\"publicationDate\":\"2024-07-14\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Accounts of Chemical Research\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.4314/mmj.v36i2.6\",\"RegionNum\":1,\"RegionCategory\":\"化学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"CHEMISTRY, MULTIDISCIPLINARY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Accounts of Chemical Research","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.4314/mmj.v36i2.6","RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"CHEMISTRY, MULTIDISCIPLINARY","Score":null,"Total":0}
Health-related quality of life and its predictors among hypertensive adults 45 years and older in rural Malawi: a population-based study
Background Hypertension is associated with impaired Health-Related Quality of Life (HRQOL), but its assessment is rarely done in the management of hypertension in Malawi. This study aimed to evaluate the HRQOL of hypertensive adults compared to normotensive individuals and suggest possible predictors of HRQOL in hypertensive adults in rural Malawi. MethodsThis was a cross-sectional study utilizing data from the 2017 Mature Adults Cohort of the Malawi Longitudinal Study for Families and Health (MLSFH-MAC). The study included 1489 adults aged 45 and above from Rumphi, Mchinji, and Balaka districts. HRQOL was measured using the Short Form 12-item (SF-12) questionnaire. Univariable logistic regression, followed by multivariable logistic regression, was used to identify independent predictors of HRQOL in hypertensive adults. A p-value of <0.05 was considered statistically significant. ResultsThe prevalence of hypertension was 44.1%. Hypertensive participants had significantly lower physical and mental HRQOL than their normotensive counterparts (p<0.05). Multiple regression analysis showed that female sex, age, presence of comorbidities, and use of antihypertensive medications were significant predictors of poor physical HRQOL. Being female was a significant predictor of poor mental HRQOL (all p-values <0.05).ConclusionIn rural Malawi, hypertensive adults presented with lower physical and mental HRQOL. Interventions aimed at improving HRQOL should focus on hypertensive adults who are female, older, on antihypertensive medications, and with comorbidities.
期刊介绍:
Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance.
Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.