Atypical artificial cells: Novel biomimetic materials for combating cancer

The functional concept of using synthetic entities to supplement or replace certain functions or structures of biological cells is realized by the development of atypical artificial cells using a bottom-up approach. Tremendous progress has been achieved over the past 5 years that focuses on the therapeutic applications of atypical artificial cells, especially in the anticancer arena. Artificial cell-based anticancer strategies have demonstrated eminent advantages over conventional anticancer tactics, with excellent biocompatibility and targeting capability. The present review commences with introducing the constructing principles and classification of artificial cells. Artificial cell-based applications in cancer prophylaxis, diagnosis, and treatment are subsequently highlighted. These stimulating outcomes may inspire the development of next-generation anticancer therapeutic strategies.