Observing the Effects of Probiotics Combined with Rexine and Peptisonide Enteral Nutrition Guidance in Postoperative Intracerebral Hemorrhage Patients

Objective: To investigate the therapeutic effects of probiotics combined with Rexine or Peptisonide enteral nutrition guidance in postoperative intracerebral hemorrhage (ICH) patients. Methods: Clinical data of 60 ICH patients treated at our hospital from May 2022 to January 2024 were retrospectively analyzed. The patients were divided into an observation group (OG) (probiotics combined with Peptisonide) and a control group (CG) (probiotics combined with Rexine), with 30 cases in each group. The comparison of neurological function scores, immunoglobulin levels, inflammation and infection markers, and adverse reactions between the two groups was conducted during the treatment process. Results: Before treatment, the two groups were comparable in terms of The National Institutes of Health Stroke Scale (NIHSS) scores, Immunoglobulin A (IgA), Immunoglobulin G (IgG), Immunoglobulin M (IgM), D-lactic acid, and Procalcitonin (PCT) levels (P>0.05). After treatment, the NIHSS scores significantly decreased in both groups, with a more pronounced reduction observed in the OG (P<0.05). Levels of IgA, IgG, and IgM significantly increased, with a more substantial rise in the OG (P<0.05). The D-lactic acid levels significantly decreased, and both the D-lactic acid and PCT levels were lower in the OG (P<0.05). The incidence of vomiting, gastric retention, and gastrointestinal bleeding did not differ significantly between the two groups (P>0.05), but the incidence of diarrhea and constipation was notably lower in the OG compared to the CG (P<0.05). Conclusion: The probiotic combined with Peptisonide enteral nutrition scheme significantly improves neurological function, enhances immunity, reduces inflammatory response, and decreases adverse reactions.