{"title":"用于治疗人类疾病的 DNA 疫苗和传递系统的未来导向与进展","authors":"Shivani Biragi, Satish Dod, Tejas Singh, Upendra Prajapati, Shaily Chaudhary","doi":"10.9734/ajrimps/2024/v13i3265","DOIUrl":null,"url":null,"abstract":"In the domain of vaccination, DNA antibodies have transformed into a striking methodology that appreciates different high grounds over ordinary vaccination modalities. A design of the vital considerations behind DNA vaccinations, their technique for action, and energy upgrades in their assessment are given in this hypothetical. Trustworthy immunity is made by DNA courses of action, which use plasmid DNA encoding antigenic proteins to move humoral and cell-safe responses. They are in like manner a secured and versatile stage for immunization considering their capacity to replicate a trademark illness without spreading disorder. DNA inoculations are dynamic against different versatile contaminations, including those achieved by microorganisms, diseases, and parasite organisms. Furthermore, updates in adjuvants, plan frameworks, and association techniques have raised their immunogenicity and adequacy. Notwithstanding the way that there have been a couple of sure new developments, enormous checks really ought to be addressed to redesign power.\" DNA inoculations, by and large, address a promising street for making state-of-the-art antibodies arranged to effectively fight emerging overwhelming risks.","PeriodicalId":502352,"journal":{"name":"Asian Journal of Research in Medical and Pharmaceutical Sciences","volume":"6 8","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2024-07-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Future-oriented and Progress in DNA Vaccine and Delivery Systems for the Treatment of Human Diseases\",\"authors\":\"Shivani Biragi, Satish Dod, Tejas Singh, Upendra Prajapati, Shaily Chaudhary\",\"doi\":\"10.9734/ajrimps/2024/v13i3265\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"In the domain of vaccination, DNA antibodies have transformed into a striking methodology that appreciates different high grounds over ordinary vaccination modalities. A design of the vital considerations behind DNA vaccinations, their technique for action, and energy upgrades in their assessment are given in this hypothetical. Trustworthy immunity is made by DNA courses of action, which use plasmid DNA encoding antigenic proteins to move humoral and cell-safe responses. They are in like manner a secured and versatile stage for immunization considering their capacity to replicate a trademark illness without spreading disorder. DNA inoculations are dynamic against different versatile contaminations, including those achieved by microorganisms, diseases, and parasite organisms. Furthermore, updates in adjuvants, plan frameworks, and association techniques have raised their immunogenicity and adequacy. Notwithstanding the way that there have been a couple of sure new developments, enormous checks really ought to be addressed to redesign power.\\\" DNA inoculations, by and large, address a promising street for making state-of-the-art antibodies arranged to effectively fight emerging overwhelming risks.\",\"PeriodicalId\":502352,\"journal\":{\"name\":\"Asian Journal of Research in Medical and Pharmaceutical Sciences\",\"volume\":\"6 8\",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2024-07-22\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Asian Journal of Research in Medical and Pharmaceutical Sciences\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.9734/ajrimps/2024/v13i3265\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Asian Journal of Research in Medical and Pharmaceutical Sciences","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.9734/ajrimps/2024/v13i3265","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
摘要
在疫苗接种领域,DNA 抗体已成为一种引人注目的方法,与普通疫苗接种方式相比,它具有不同的优势。本假说对 DNA 疫苗背后的重要考虑因素、其作用技术和评估中的能量提升进行了设计。可信赖的免疫力是由 DNA 行动方案产生的,它使用编码抗原蛋白的 DNA 质粒来调动体液和细胞安全反应。考虑到它们能够复制商标性疾病而不会传播疾病,因此它们同样是一种安全、多用途的免疫阶段。DNA 接种能有效抵御各种不同的污染,包括微生物、疾病和寄生生物造成的污染。此外,佐剂、计划框架和关联技术的更新也提高了它们的免疫原性和充分性。尽管已经取得了一些肯定的新进展,但仍需进行大量检查,以重新设计免疫力"。总的来说,DNA接种为制造最先进的抗体提供了一条大有可为的道路,可有效对抗新出现的巨大风险。
Future-oriented and Progress in DNA Vaccine and Delivery Systems for the Treatment of Human Diseases
In the domain of vaccination, DNA antibodies have transformed into a striking methodology that appreciates different high grounds over ordinary vaccination modalities. A design of the vital considerations behind DNA vaccinations, their technique for action, and energy upgrades in their assessment are given in this hypothetical. Trustworthy immunity is made by DNA courses of action, which use plasmid DNA encoding antigenic proteins to move humoral and cell-safe responses. They are in like manner a secured and versatile stage for immunization considering their capacity to replicate a trademark illness without spreading disorder. DNA inoculations are dynamic against different versatile contaminations, including those achieved by microorganisms, diseases, and parasite organisms. Furthermore, updates in adjuvants, plan frameworks, and association techniques have raised their immunogenicity and adequacy. Notwithstanding the way that there have been a couple of sure new developments, enormous checks really ought to be addressed to redesign power." DNA inoculations, by and large, address a promising street for making state-of-the-art antibodies arranged to effectively fight emerging overwhelming risks.