男性雄激素性脱发患者口服小剂量米诺地尔的副作用频率评估

IF 1.4 Q3 DERMATOLOGY
Leila David Bloch, Rafaelly Mayara Dantas Carlos
{"title":"男性雄激素性脱发患者口服小剂量米诺地尔的副作用频率评估","authors":"Leila David Bloch, Rafaelly Mayara Dantas Carlos","doi":"10.1159/000539969","DOIUrl":null,"url":null,"abstract":"Introduction: Hair loss is a very common complaint in dermatologists’ offices, requiring the use of proven safe and effective therapies to improve the condition without jeopardizing patients’ health and well-being. Methods: We selected 100 male patients with androgenetic alopecia beginning treatment with low dose oral minoxidil to observe incidence and frequency of side effects. Results: The side-effects/symptoms observed in the assessed patients included body and facial hypertrichosis (most incidents), lower legs edema, periorbital edema, fatigue, tachycardia, and insomnia. Dizziness, hypotension, respiratory changes, and diarrhea were expected although not found in the assessed participants. No life-threatening adverse effects were observed. Conclusion: The doses administered in current research of oral minoxidil presented good safety profile as hair loss treatment, with the most incident side-effect being related to hypertrichosis. Systemic side-effects were infrequent.","PeriodicalId":21844,"journal":{"name":"Skin Appendage Disorders","volume":null,"pages":null},"PeriodicalIF":1.4000,"publicationDate":"2024-07-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Side Effects’ Frequency Assessment of Low Dose Oral Minoxidil in Male Androgenetic Alopecia Patients\",\"authors\":\"Leila David Bloch, Rafaelly Mayara Dantas Carlos\",\"doi\":\"10.1159/000539969\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Introduction: Hair loss is a very common complaint in dermatologists’ offices, requiring the use of proven safe and effective therapies to improve the condition without jeopardizing patients’ health and well-being. Methods: We selected 100 male patients with androgenetic alopecia beginning treatment with low dose oral minoxidil to observe incidence and frequency of side effects. Results: The side-effects/symptoms observed in the assessed patients included body and facial hypertrichosis (most incidents), lower legs edema, periorbital edema, fatigue, tachycardia, and insomnia. Dizziness, hypotension, respiratory changes, and diarrhea were expected although not found in the assessed participants. No life-threatening adverse effects were observed. Conclusion: The doses administered in current research of oral minoxidil presented good safety profile as hair loss treatment, with the most incident side-effect being related to hypertrichosis. Systemic side-effects were infrequent.\",\"PeriodicalId\":21844,\"journal\":{\"name\":\"Skin Appendage Disorders\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":1.4000,\"publicationDate\":\"2024-07-23\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Skin Appendage Disorders\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1159/000539969\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"DERMATOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Skin Appendage Disorders","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1159/000539969","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"DERMATOLOGY","Score":null,"Total":0}
引用次数: 0

摘要

简介:脱发是皮肤科医生诊室中非常常见的主诉病症,需要使用经证实安全有效的疗法来改善脱发状况,同时又不损害患者的健康和福祉。治疗方法我们挑选了 100 名男性雄激素性脱发患者,开始使用小剂量口服米诺地尔治疗,观察副作用的发生率和频率。结果在接受评估的患者中观察到的副作用/症状包括身体和面部多毛(最多)、小腿水肿、眶周水肿、疲劳、心动过速和失眠。预计会出现头晕、低血压、呼吸系统变化和腹泻,但未在接受评估的参与者中发现。没有观察到危及生命的不良反应。结论在目前的研究中,口服米诺地尔作为脱发治疗药物的剂量具有良好的安全性,最常见的副作用与多毛症有关。全身性副作用并不常见。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Side Effects’ Frequency Assessment of Low Dose Oral Minoxidil in Male Androgenetic Alopecia Patients
Introduction: Hair loss is a very common complaint in dermatologists’ offices, requiring the use of proven safe and effective therapies to improve the condition without jeopardizing patients’ health and well-being. Methods: We selected 100 male patients with androgenetic alopecia beginning treatment with low dose oral minoxidil to observe incidence and frequency of side effects. Results: The side-effects/symptoms observed in the assessed patients included body and facial hypertrichosis (most incidents), lower legs edema, periorbital edema, fatigue, tachycardia, and insomnia. Dizziness, hypotension, respiratory changes, and diarrhea were expected although not found in the assessed participants. No life-threatening adverse effects were observed. Conclusion: The doses administered in current research of oral minoxidil presented good safety profile as hair loss treatment, with the most incident side-effect being related to hypertrichosis. Systemic side-effects were infrequent.
求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
CiteScore
2.00
自引率
10.00%
发文量
69
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信