在接受利福平治疗的骨科器械相关感染患者的皮肤和鼻腔中出现耐利福平葡萄球菌

IF 1.8 Q3 INFECTIOUS DISEASES

Journal of Bone and Joint Infection Pub Date : 2024-07-24 DOI:10.5194/jbji-9-191-2024

Alexandra Wallimann, Yvonne Achermann, Ciara Ferris, Mario Morgenstern, Martin Clauss, Vincent Stadelmann, Hannes A Rüdiger, L. O’Mahony, T. F. Moriarty

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引用次数: 0

摘要

摘要利福平是治疗葡萄球菌生物膜感染的主要抗生素。在这项试验性研究中，我们发现接受利福平治疗骨科器械相关感染（ODRI）的患者在治疗期间定植了耐利福平葡萄球菌，这种情况在停止治疗后持续长达两个月。

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Emergence of rifampicin-resistant staphylococci on the skin and nose of rifampicin-treated patients with an orthopaedic-device-related infection

Abstract. Rifampicin is a key antibiotic in the treatment of staphylococcal biofilm infections. In this pilot study, we found that patients who received rifampicin for treatment of an orthopaedic-device-related infection (ODRI) were colonized with rifampicin-resistant staphylococci during treatment and this persisted for up to 2 months after cessation of treatment.

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来源期刊

Journal of Bone and Joint Infection Medicine-Surgery

CiteScore

3.70

自引率

0.00%

发文量

审稿时长

12 weeks